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    Glossary Sulfation

    biochemical process adding sulfate groups to molecules

    Sulfation is a biochemical process where a sulfate group (SO₄) is added to molecules, such as hormones, drugs, or neurotransmitters. This modification often alters the molecule's function, solubility, or how it is metabolized and excreted by the body. In the context of hair biology, sulfation can influence the activity of certain proteins and enzymes involved in hair growth and health.

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    Research 30 of 595

    1. Sulfotransferases, sulfatases and formylglycine-generating enzymes: a sulfation fascination Current Opinion in Chemical Biology · 2008 · 83 citations
    2. Sulfation of minoxidil by human liver phenol sulfotransferase Biochemical Pharmacology · 1990 · 68 citations
    3. Sulfation of minoxidil by liver sulfotransferase Biochemical Pharmacology · 1982 · 66 citations
    4. Sulfation of minoxidil by multiple human cytosolic sulfotransferases Chemico-Biological Interactions · 1998 · 59 citations
    5. Enzymatic and non-enzymatic sulfation mechanisms in the biological actions of minoxidil Biochemical Pharmacology · 1993 · 53 citations
    6. Sulphation catalysed by the human cytosolic sulphotransferases - chemical defence or molecular terrorism? Human & Experimental Toxicology · 1996 · 48 citations
    7. Sulfation of minoxidil by human platelet sulfotransferase Clinica Chimica Acta · 1987 · 39 citations
    8. Sulfation of minoxidil in keratinocytes and hair follicles. PubMed · 1989 · 19 citations
    9. Sulfation of Minoxidil in Keratinocytes and Hair Follicles and the Stimulatory Effect of Minoxidil on the Biosynthesis of Glycosaminoglycans Annals of the New York Academy of Sciences · 1991 · 5 citations
    10. Summation and recommendations for the safe and effective use of topical and oral minoxidil Journal of the American Academy of Dermatology · 2025 · 5 citations
    11. Minoxidil Sulfation in the Hair Follicle Skin Pharmacology and Physiology · 1994 · 32 citations
    12. Selective inhibition of glucuronidation and sulfation in vitro and in vivo European Journal of Pharmacology · 1990 · 1 citations
    13. Polysaccharides from Traditional Chinese Medicines: Extraction, Purification, Modification, and Biological Activity Molecules · 2016 · 125 citations
    14. Phenolsulphotransferase: localization in kidney during human embryonic and fetal development Histochemical Journal · 1994 · 18 citations
    15. Characterization of Recombinant Human Liver Thermolabile Phenol Sulfotransferase with Minoxidil as the Substrate Biochemical and Biophysical Research Communications · 1995 · 16 citations
    16. Purification and characterization of rat liver minoxidil sulphotransferase Biochemical Journal · 1990 · 29 citations
    17. Solubility of minoxidil in binary mixture of ethanol + water at various temperatures Physics and chemistry of liquids · 2018 · 20 citations
    18. Minoxidil as a Prodrug: Review of Chemical, Pharmacological, and Technological Aspects in Alopecia Therapeutics Mini-Reviews in Medicinal Chemistry · 2026
    19. Solubilities of Flutamide, Dutasteride, and Finasteride as Antiandrogenic Agents, in Supercritical Carbon Dioxide: Measurement and Correlation Journal of Chemical & Engineering Data · 2009 · 19 citations
    20. Application of Polarisable Continuum Modelling to assess Minoxidil solubility in mixed solvents Physics and Chemistry of Liquids · 2022
    21. Structural studies of two solid steroid compounds Durham e-Theses (Durham University) · 2006 · 2 citations
    22. Production of GJycosaminoglycans by Rat Hair Follicle Cells in Vitro Australian Journal of Biological Sciences · 1981 · 4 citations
    23. Characterization of recombinant human liver dehydroepiandrosterone sulfotransferase with minoxidil as the substrate Biochemical Pharmacology · 1997 · 13 citations
    24. Sulfated hyaluronan‐containing artificial extracellular matrices promote proliferation of keratinocytes and melanotic phenotype of melanocytes from the outer root sheath of hair follicles Journal of Biomedical Materials Research Part A · 2019 · 8 citations
    25. Rice Bran Polysaccharides: Structure, Modification, Bioactivity, and Application Potential in Food and Health Systems Foods · 2026
    26. Structural Study of Polymorphs and Solvates of Finasteride Journal of Pharmaceutical Sciences · 2007 · 61 citations
    27. Antioxidant Activities of Natural Polysaccharides and Their Derivatives for Biomedical and Medicinal Applications Antioxidants · 2022 · 130 citations
    28. Localization of Minoxidil Sulfotransferase in Rat Liver and the Outer Root Sheath of Anagen Pelage and Vibrissa Follicles Journal of Investigative Dermatology · 1991 · 46 citations
    29. Combinatorial Biosynthesis of Sulfated Benzenediol Lactones with a Phenolic Sulfotransferase from Fusarium graminearum PH-1 mSphere · 2020 · 22 citations
    30. Experimental and computational approaches for measuring minoxidil solubility in propylene glycol + water mixtures at different temperatures Journal of Molecular Liquids · 2019 · 7 citations