1 citations
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January 2004 in “Cosmetics and toiletries” Polyquaternium-64 helps damaged hair look healthy again.
February 2006 in “Inpharma Weekly”
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This study indicates that MPZL3 negatively regulates sebaceous gland size in mice by controlling sebocyte proliferation, with implications for disorders like acne and psoriasis.
48 citations
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February 2010 in “Molecular biology reports” This study found that KAP7.1 and KAP8.2 genes were significantly more expressed in secondary hair follicles than primary follicles, suggesting their role in regulating cashmere fiber diameter.
2 citations
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December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that SYP123 and VAMP727 are involved in the secretion and transport of inner cell wall components, which is crucial for hardening the root hair shank in Arabidopsis.
8 citations
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January 2013 in “genesis” This study identified a new transcriptional repressor, Zfp157, as a target of Stat6 in the mammary gland, expressing in various tissues during mouse embryogenesis and adulthood.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This study presents the design of an autonomous bioregeneration chamber that aims to extend human lifespan to 130-150 years by optimizing biological and environmental conditions, suggesting that a longer healthspan is possible through technological, nutritional, and socio-economic interventions.
January 2024 in “Wiadomości Lekarskie” This article reviews the potential applications of Point of Care procedures in radiology, discussing their ability to enhance the speed of diagnosis and treatment but does not report new results.
April 2016 in “Journal of The American Academy of Dermatology” Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.
July 2024 in “Journal of Investigative Dermatology” PH-762 shows promise in treating skin cancer by effectively targeting and silencing PD-1 in tumors with minimal side effects.
15 citations
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January 1991 in “Mammalian Genome”
This invention reports piperazine derivatives as potent inhibitors of type 3 17β-hydroxysteroid dehydrogenase, suggesting potential therapeutic applications in treating prostate cancer, acne, and androgenic alopecia.
This article discusses the role of epimorphin as a key morphoregulator for various epithelial cells in tubulogenesis and reports no experimental results on its signaling pathways.
May 2025 in “Science Advances” In this study, researchers reported that hair follicle stem cells maintain quiescence through a PIEZO1-dependent mechanism that senses mechanical forces and translates them into localized calcium influx, involving a transcriptional network that regulates cell adhesion and cytoskeleton-related genes.
June 2023 in “British Journal of Dermatology” This pilot study found that night shift workers showed fewer signs of wrinkle formation compared to day workers, but there were no significant differences in DNA amplification or collagen percentage.
April 2026 in “Human Genome Variation” In this study, researchers identified a recurrent MBTPS2 splice-site variant as a mutational hotspot in IFAP syndrome across diverse families, with phenotype severity suggesting the influence of additional modifiers.
2 citations
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January 2023 in “Uro” This study found that both a proprietary ultrahigh-pressure extract and a hexanic extract of saw palmetto showed comparable inhibition of 5α-reductase, suggesting similar potential for managing symptoms of benign prostatic hyperplasia.
39 citations
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August 2022 in “Pharmaceutics” This study found that the combination of letrozole and quercetin loaded in spanlastics showed enhanced cytotoxicity and other anticancer effects against MCF-7 breast cancer cells compared to individual treatments.
November 2022 in “Journal of Investigative Dermatology” This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.
June 2026 in “Journal of Nanobiotechnology” This study reported that human umbilical cord mesenchymal stem cell-derived exosomes may promote hair regeneration and thickness in androgenic alopecia by modulating cellular pathways in hair growth, including increasing hair density and diameter, as observed in a mouse model and an exploratory clinical trial.
The document's conclusion cannot be summarized because the content is not available.
5 citations
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October 2021 in “Journal of the American Academy of Dermatology” PRAME helps distinguish between benign and malignant skin cells in most cases.
January 2026 in “Journal of Emerging Technologies and Innovative Research” This study reported that zinc oxide nanoparticles synthesized using Tridax procumbens leaf extract demonstrated significant antibacterial and anticancer activity, showing potential for applications in biomedical and pharmaceutical fields.
4 citations
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October 2007 in “PubMed” This study found that the PQ-70 shampoo formulation demonstrated the highest Hair Humidity Resistance Factor, indicating superior anti-frizz performance compared to other tested shampoos.
September 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” This study observed that treating hair follicles with BM15766 and 7DHC led to structural damage, disrupted cellular organization, reduced expression of key genes and proteins, and increased apoptosis, in contrast to controls, indicating detrimental effects on hair follicle integrity.
4 citations
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November 2017 in “Journal of Cosmetic Dermatology” This study found that polyquaternium-68 at pH 9 achieved the greatest hair deposition, while polyquaternium-44 demonstrated the best wash resistance at pH 6.
September 2025 in “Cancer Innovation” This study argues for "clinical trial re-innovation," highlighting new designs like basket, umbrella, and platform trials that incorporate biomarker technologies to meet the dynamic needs of precision medicine, potentially enabling more effective, patient-specific treatments and overcoming limitations of traditional disease-centered trials.
July 2016 in “Dermatologie pro praxi” This article discusses the use of Espumil foam base in pharmacies for preparing dermatological medications and reports no new clinical results.
August 2023 in “Zenodo (CERN European Organization for Nuclear Research)”
78 citations
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June 2013 in “Science” This study found that mice lacking the Sept4/ARTS gene had more hair follicle stem cells and improved wound healing, suggesting apoptosis regulation as a potential target in regenerative medicine.