Green Fabrication of ZnO Nanoparticles from Tridax Procumbens Leaf Extract: Antimicrobial and Cytotoxic Evaluation on MCF7 and A549 Cells

This study successfully synthesized zinc oxide nanoparticles using Tridax procumbens leaf extract through a green synthesis method. The nanoparticles, characterized by various analytical techniques, showed a quasi-spherical morphology with sizes ranging from 7-15 nm. They exhibited significant antibacterial activity, particularly against P. aeruginosa, and demonstrated strong cytotoxic effects with IC50 values of 95.5 µg/mL for A459 cells and 29.72 µg/mL for MCF-7 cells. These results suggest that TP-ZnO nanoparticles have promising potential for applications in biomedical and pharmaceutical fields due to their antimicrobial and anticancer properties.