Green Synthesis of ZnO and Mg-Doped ZnO Nanoparticles Using Ferulago Angulata Plant Extract and Its Effect on Second-Degree Burn Wound Healing
September 2025
in “
Cell Biochemistry and Function
”
ZnO nanoparticles Mg-doped ZnO nanoparticles Ferulago angulata antioxidant activity cytotoxicity antibacterial properties antifungal properties wound healing collagenization epithelialization hair follicle formation zinc oxide nanoparticles magnesium-doped zinc oxide nanoparticles hair growth skin regeneration
TLDR Mg-doped ZnO nanoparticles from plant extract effectively heal second-degree burns.
The study investigated the synthesis and therapeutic effects of zinc oxide nanoparticles (ZnO NPs) and magnesium-doped ZnO NPs using Ferulago angulata plant extract for treating second-degree burn wounds. The nanoparticles were characterized and tested for antioxidant, cytotoxic, antibacterial, and antifungal properties. The results showed that a 0.1% concentration of Mg-doped ZnO NPs was most effective, promoting complete wound healing and improved skin condition after 21 days, including increased hair follicle formation and presence of sebaceous glands, indicating enhanced healing and skin regeneration.
