6 citations
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November 2022 in “Journal of Tissue Engineering and Regenerative Medicine” This study found that while zebularine did not significantly accelerate wound healing, it improved the quality of restored skin in mice, suggesting potential for further research into epigenetic inhibitors.
4 citations
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January 2024 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This consensus statement outlines a treatment algorithm for alopecia areata, detailing systemic treatment indications and options, including EMA-approved medications baricitinib and ritlecitinib for severe cases, as well as other off-label treatments and adjuvant therapies like oral minoxidil.
7 citations
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October 2019 in “Annals of palliative medicine” This review examines the incidence and management of dermatologic adverse effects from FDA-approved oral targeted cancer therapies, highlighting frequent occurrences like rashes and rarer severe conditions such as Stevens-Johnson Syndrome.
45 citations
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January 2020 in “International Journal of Molecular Sciences” This review discusses the potential of plant polyphenols to overcome multidrug resistance in various solid cancers and reports no new experimental results; further research is suggested.
March 2026 in “Dermatology and Therapy” This study identified distinct plasma miRNA profiles in alopecia areata that may aid in diagnosis and therapy, but further validation is needed to confirm these exploratory findings.
31 citations
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January 2017 in “Phytotherapy Research” This review reports on the traditional and ethnopharmacological uses of Ziziphus jujuba Mills, noting its increasing global popularity for treating various ailments, but highlights that its acceptance into the European Pharmacopoeia remains unresolved due to scientific and regulatory challenges.
2 citations
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February 2020 in “International Journal of Research in Pharmaceutical Sciences” This review compiles evidence on the health benefits of Ziziphus mauritiana, covering its traditional uses and pharmacological effects, but reports no new experimental results.
37 citations
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January 2015 in “Journal of Clinical and Experimental Dentistry” This animal study found that both systemic and topical forms of Zizyphus jujuba extract were associated with reduced severity of oral mucositis in golden hamsters treated with 5-fluorouracil.
January 2020 in “Dépôt Institutionnel de lUniversité de Tlemcen” This article is primarily an acknowledgment and dedication section of a thesis, expressing gratitude to individuals involved in its completion and reports no new research findings.
January 2024 in “International journal of pharmaceutical sciences review and research” This review paper critically evaluates the pharmacological and toxicological effects of Ziziphus mauritiana, a plant with traditional medicinal use, highlighting its anxiolytic, antioxidant, antimicrobial, anti-cancer, anti-diabetic, and anti-ulcer properties attributed to its rich phytochemical composition.
73 citations
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March 2010 in “Food and Chemical Toxicology” This study found that Zizyphus jujuba essential oil enhanced hair growth in mice, with the 1% and 10% concentrations showing increased hair length compared to control.
72 citations
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November 2020 in “Frontiers in Pharmacology” This review highlights potential benefits of jujube fruits on blood health, suggesting they might aid anemia prevention or treatment by supporting erythropoiesis and immune regulation, based on evidence from cell and animal studies.
November 2020 in “Food Science and Technology” Ziziphus jujube Mill extract can naturally protect corn from fungi.
15 citations
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September 2013 in “Pharmaceutical Biology” This study found that Zizyphus jujuba fruit aqueous extract may reduce nephrotoxicity caused by ibuprofen in rats by lowering serum urea and creatinine and improving kidney antioxidant enzyme activities.
This study investigated the effects of ethanol leaf extracts from Ziziphus jujuba and Eclipta alba on cognitive impairments in diabetic rats, finding significant improvements in learning and memory with these treatments, along with decreased blood glucose levels over 21 days.
October 2023 in “Journal of food chemistry & nanotechnology” In this review, the authors highlighted the medicinal potential of Ziziphus jujuba seeds, emphasizing their antioxidant, antimicrobial, and anti-inflammatory properties, and called for further research to better understand their therapeutic effects and mechanisms.
June 2024 in “Plastic & Reconstructive Surgery Global Open” This source reports that the JOLT technique using HA fillers is effective in lifting and tightening the lower face and neck, camouflaging the jowl, and improving marionette lines and the mandibular border.
9 citations
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December 2011 in “Potravinarstvo Slovak Journal of Food Sciences” This study identified significant morphological and sensory differences among 19 genotypes of Ziziphus jujube Mill. grown at the Slovak University of Agriculture, suggesting potential applications in organic agriculture and other practices.
38 citations
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January 2013 in “Analyst” This study identified the main secondary metabolites in Ziziphus jujuba seeds and confirmed that UPLC-MS/MS and GC-MS effectively demonstrate their pharmaceutical quality.
9 citations
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August 2014 in “Journal of The Korean Society of Food Science and Nutrition” This study found that Zizyphus jujuba, especially when fermented with Saccharomyces cerevisiae, showed strong antioxidative activity and effectively promoted hair regrowth and prevented hair loss in a mouse model.
December 2023 in “Medical & Clinical Case Reports Journal” This case study reported significant hair regrowth in a young female patient with alopecia areata after 60 days of Ayurvedic treatment, including leech therapy and herbal medicines, demonstrating its potential effectiveness according to the authors' observations.
1 citations
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January 2024 in “Journal of Cosmetic Dermatology” In this study, JAUN soap was found to improve skin conditions, such as moisture, elasticity, and cleansing effectiveness, without adverse reactions, suggesting its potential as a safe and effective ingredient for functional cosmetics.
September 2025 in “Clinical Cosmetic and Investigational Dermatology” In this randomized, placebo-controlled study, Kūlaris supplementation significantly improved quality of life for participants with mild-to-severe acne over 12 weeks, though no significant changes in general skin health measures were observed compared to placebo.
January 2018 in “International Journal of Advances in Scientific Research and Engineering” This study presents a new automated method for measuring total phenolic compounds in Ziziphus Jujuba fruit extract, showing high precision and potential applications in health and environmental sciences.
1 citations
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January 2019 in “Clinical, Cosmetic and Investigational Dermatology” In this study, a gel containing extracts from Coffea arabica and Larrea divaricata was found to significantly thicken eyebrows and eyelashes in most premenopausal and postmenopausal women, without causing adverse effects, but showed no statistical difference from a placebo in overall hair growth.
July 2025 in “Journal of Investigative Dermatology” Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.
1 citations
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January 2013 in “African Journal of Pharmacy and Pharmacology” This study found that ultrasound assisted microwave extraction was more efficient than other methods for extracting luteolin from Eclipta prostrata, reducing extraction time and simplifying the process.
December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This case study reported marked improvement in hair loss symptoms for a 30-year-old woman using Ayurvedic leech therapy (Jalaukavacharana), highlighting its potential as a gentle and minimally invasive alternative to conventional alopecia treatments.
1 citations
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June 2023 in “Ethnobotany research and applications” This review examined the medicinal properties of the Ziziphus plant species, highlighting their traditional use in treating various conditions and their bioactive compounds with potential anticancer, antimicrobial, and anti-diabetic effects. The authors concluded that Ziziphus species, particularly jujube, have promising pharmacological activities warranting further investigation.