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Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.

Ectodysplasin signaling is crucial for skin appendage development, requiring specific doses and durations.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.

Identified genes linked to male-pattern baldness may help develop new treatments.

Colorectal cancer development involves both genetic changes and epigenetic alterations like DNA methylation and microRNA changes.

Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.

Certain DNA regions in alpacas are linked to fiber diameter.

Dihydrotestosterone makes arteries stiffer in female mice by reducing estrogen receptor expression.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.

Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Scientists created a functional 3D skin system from stem cells that can be transplanted into wounds.

Rare ULBP3 gene changes may raise the risk of Alopecia areata, a certain FAS gene deletion could cause a dysfunctional protein in an immune disorder, and having one copy of a specific genetic deletion is okay, but two copies cause sickle cell disease.

The mouse hairy ears mutation causes longer ear hair due to changes in gene expression.

Acute leukemias with the Philadelphia chromosome may be biphenotypic, and identifying this is important for proper treatment.

The document concludes that permanent hair loss conditions are complex, require early specific treatments, and "secondary permanent alopecias" might be a more accurate term than "secondary cicatricial alopecia."

DNA profiling in forensics has improved, but predicting physical traits and ancestry from DNA has limitations and requires ethical consideration.

Skin issues can indicate immune system problems.

Identical twins had different symptoms because one had more cells with an extra chromosome fragment in different tissues.

Androgens can both increase and decrease hair growth in different parts of the body.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

The transgene likely activated an oncogene or interrupted a tumor suppressor gene, causing melanoma in mice.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Keratin 79 marks a new group of cells that are key for creating and repairing the hair follicle's structure.

WNT10B is linked to cancer development and affects survival and disease progression in various cancers.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.