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Caffeine in cosmetics may reduce cellulite, protect skin, and stimulate hair growth, but more research is needed on its use and effects.

Estrogen therapy can reduce skin aging but has cancer risks.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Microneedles help improve skin appearance and deliver skin treatments effectively, but safety concerns need more research and regulation.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.

Skin surface lipids are important for skin health and altering them could help prevent aging and treat skin conditions.

Fullerenes show potential in skin care but need more safety research.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Antioxidants can benefit skin health but should be used carefully to avoid negative effects.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Different types of facial fat affect aging and treatment outcomes; more research is needed to enhance anti-aging procedures.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.

Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.

Ginseng and its compounds may help hair growth and prevent hair loss, but more human trials are needed to confirm this.

Eclipta alba has many health benefits and contains compounds with potential for drug development.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

Fractional laser resurfacing is effective and safe for skin treatment, with benefits like less downtime and a low risk of adverse events.

Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Nonablative radiofrequency treatments, especially microneedle and fractional types, can improve acne scars by 25%–75% after 3-4 sessions, with full results in 3 months and some side effects.

Dutasteride-containing mesotherapy effectively treats female hair loss, improving density and thickness with minimal side effects.

Plant-based ingredients are effective and safe for modern skincare products.

Human hair has a protective lipid layer that can be damaged by moisture and treatments, affecting hair growth and health.