July 2023 in “International Journal of Cosmetic Science” Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.
The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.
Using enzymes to link proteins makes hair repair treatments more effective and long-lasting.
February 2023 in “European biophysics journal” November 2022 in “Animal Bioscience” Adding methionine to a low-protein diet helps Angora rabbits grow better fur.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
January 2016 in “Journal of clinical & experimental dermatology research” New methods can diagnose hair loss by examining the scalp and can treat it with a mix of oral and topical medications, along with cosmetic procedures like hair transplants.
854 citations,
February 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
235 citations,
July 1999 in “Journal of biological chemistry/The Journal of biological chemistry” Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.
231 citations,
December 1999 in “Journal of Investigative Dermatology” Hair follicle size is mainly influenced by the number of cells and extracellular matrix volume, with cell number having a larger impact.
117 citations,
August 2005 in “Ultramicroscopy” Human hair's strength and flexibility vary by ethnicity, damage, and treatment.
115 citations,
August 2014 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” Human hair keratin can be used in many medical applications.
107 citations,
June 1997 in “PubMed” EGFR is essential for normal hair development and follicle differentiation.
100 citations,
December 2002 in “Journal of biological chemistry/The Journal of biological chemistry” Researchers mapped and categorized specific keratin-associated protein genes on human chromosome 21q22.1.
94 citations,
July 2003 in “Journal of biological chemistry/The Journal of biological chemistry” EGF controls hair growth by regulating hair follicles' growth phases.
86 citations,
April 2009 in “Journal of anatomy” Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.
75 citations,
September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
69 citations,
January 2002 in “Journal of biomedical optics” Dyes can penetrate human skin and hair follicles up to 1.2 mm deep and the sebaceous gland can store dye; Indocyanine Green lotion was made for safe dyeing and monitoring.
63 citations,
February 2017 in “ACS biomaterials science & engineering” Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.
61 citations,
July 2011 in “PLOS ONE” Spermidine may help reduce hair loss and deserves further testing as a treatment.
56 citations,
January 1996 in “Journal of Forensic Sciences” Dye enters hair at the edges of cuticle cells and penetrates more from water than alcohol-based solutions.
55 citations,
March 2010 in “Aging” Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
53 citations,
January 2013 in “Journal of toxicologic pathology” The project created a standardized system for classifying skin lesions in lab rats and mice.
51 citations,
September 2012 in “Biomacromolecules” Disulfide bonds make keratin in hair stronger and tougher.
51 citations,
January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” Scientists discovered a unique hair protein, KAP24.1, with a special structure, found only in the upper part of hair cuticles.
50 citations,
February 2013 in “BMC evolutionary biology” Cetaceans lost hair due to changes in the Hr and FGF5 genes.
50 citations,
January 2007 in “PubMed” Minoxidil 2% and 5% are common treatments for female pattern hair loss, with other options including anti-androgens, oral contraceptives, and hair transplantation.
46 citations,
June 2013 in “Journal of structural biology” High glycine–tyrosine keratin-associated proteins help make hair strong and maintain its shape.
45 citations,
October 2008 in “Cytokine & Growth Factor Reviews” Activins and follistatins, part of the TGFβ family, are crucial for hair follicle development and skin health, affecting growth, repair, and the hair cycle.
43 citations,
January 2016 in “Cellular physiology and biochemistry” Epidermal Growth Factor helps hair follicle cells grow and move by activating a specific cell signaling pathway.