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    Glossary Wnt7a

    protein crucial for hair follicle development and growth

    Wnt7a is a protein that plays a crucial role in the development and growth of hair follicles. It is part of the Wnt signaling pathway, which is essential for cell communication and regulation during embryonic development and tissue regeneration. In the context of hair, Wnt7a helps to stimulate the growth and maintenance of hair follicles, making it a key factor in understanding conditions like alopecia.

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    1. Wnt Signaling in Skin Development, Homeostasis, and Disease Cold Spring Harbor Perspectives in Biology · 2012 · 260 citations
    2. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    3. Treatment of MSCs with Wnt1a-conditioned medium activates DP cells and promotes hair follicle regrowth Scientific Reports · 2014 · 61 citations
    4. A Conditioned Medium of Umbilical Cord Mesenchymal Stem Cells Overexpressing Wnt7a Promotes Wound Repair and Regeneration of Hair Follicles in Mice Stem Cells International · 2017 · 36 citations
    5. Wnt1a maintains characteristics of dermal papilla cells that induce mouse hair regeneration in a 3D preculture system Journal of Tissue Engineering and Regenerative Medicine · 2015 · 23 citations
    6. Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases Journal of Cellular Biochemistry · 2019 · 16 citations
    7. Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development Development · 2022 · 7 citations
    8. Narrowband UVB treatment induces expression of WNT7B, WNT10B and TCF7L2 in psoriasis skin Archives of Dermatological Research · 2019 · 5 citations
    9. Dietary Vitamin A Dose Dependently Regulates BMP4 and WNT7A in Hair Follicles The FASEB Journal · 2017
    10. Wnt7a can up-regulates cell adhesion related protein fibronectin expression and promotes cell proliferation in corneal epithelial cells 2023
    11. Wnt signaling induces epithelial differentiation during cutaneous wound healing BMC Cell Biology · 2006 · 159 citations
    12. Control of hair follicle cell fate by underlying mesenchyme through a CSL–Wnt5a–FoxN1 regulatory axis Genes & development · 2010 · 95 citations
    13. Wnt signaling in skin organogenesis Organogenesis · 2008 · 72 citations
    14. WNT5A drives interleukin-6-dependent epithelial–mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis Burns & Trauma · 2022 · 56 citations
    15. Inhibition of Wnt/β‐catenin pathway promotes regenerative repair of cutaneous and cartilage injury The FASEB Journal · 2015 · 41 citations
    16. Liposomal honokiol promotes hair growth via activating Wnt3a/β-catenin signaling pathway and down regulating TGF-β1 in C57BL/6N mice Biomedicine & Pharmacotherapy · 2021 · 31 citations
    17. Identification of transcriptional targets of Wnt/β-catenin signaling in dermal papilla cells of human scalp hair follicles: EP2 is a novel transcriptional target of Wnt3a Journal of Dermatological Science · 2010 · 29 citations
    18. Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier Journal of Investigative Dermatology · 2017 · 23 citations
    19. Adenovirus-Mediated Wnt5a Expression Inhibits the Telogen-To-Anagen Transition of Hair Follicles in Mice International journal of medical sciences · 2013 · 19 citations
    20. Wnt5a Suppresses β-catenin Signaling during Hair Follicle Regeneration International Journal of Medical Sciences · 2016 · 16 citations
    21. Hair regrowth following a Wnt- and follistatin containing treatment: safety and efficacy in a first-in-man phase 1 clinical trial. PubMed · 2011 · 16 citations
    22. Isoxazole 9 (ISX9), a small molecule targeting Axin, activates Wnt/β‐catenin signalling and promotes hair regrowth British Journal of Pharmacology · 2023 · 11 citations
    23. Regulatory Processes of the Canonical Wnt/β-Catenin Pathway and Photobiomodulation in Diabetic Wound Repair International Journal of Molecular Sciences · 2022 · 11 citations
    24. Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway Oncotarget · 2017 · 11 citations
    25. Cthrc1 deficiency aggravates wound healing and promotes cardiac rupture after myocardial infarction via non-canonical WNT5A signaling pathway International Journal of Biological Sciences · 2023 · 9 citations
    26. LncRNA-599554 sponges miR-15a-5p to contribute inductive ability of dermal papilla cells through positive regulation of the expression of Wnt3a in cashmere goat Electronic Journal of Biotechnology · 2020 · 6 citations
    27. Differential effects of Wnt5a on the proliferation, differentiation and inflammatory response of keratinocytes Molecular Medicine Reports · 2017 · 6 citations
    28. A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 5 citations
    29. Isolation and characterization of recombinant murine Wnt3a Protein Expression and Purification · 2014 · 3 citations
    30. Dynamic Wnt5a expression in murine hair follicle cycle and its inhibitory effects on follicular Asian Pacific journal of tropical medicine · 2014 · 3 citations