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Most women with PCOS have high levels of male hormones, and free testosterone is the best marker for this.

Hormones, especially androgens, play a big role in acne, but most acne sufferers don't have a hormone disorder. Hormonal treatments, including birth control pills, can be very effective for women whose acne doesn't improve with regular treatments.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

The research identified various cell types in mouse and human teeth, which could help in developing dental regenerative treatments.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Animals that change color with the seasons mainly do so in response to daylight changes, but climate change is causing camouflage problems that may require evolutionary changes.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

New treatments targeting specific genes show promise for treating keratin disorders.

Lowering testosterone speeds up wound healing in male mice.

Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

Skin-derived precursors in hair follicles come from different origins but function similarly.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

The document concludes that assessing hair follicle damage due to cyclophosphamide in mice involves analyzing structural changes and suggests a scoring system for standardized evaluation.

Activating TRPV3 stops human hair growth.

Formyl-peptide receptor agonists could be new anti-inflammatory drugs.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

Laminin-511 is crucial for early hair growth and maintaining important hair development signals.

Scientists turned mouse stem cells into skin cells that can grow into skin layers and structures.

Nerves and chemicals in the body can affect hair growth and loss.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.