118 citations
,
June 1993 in “Journal of Biological Chemistry” This study found that mouse and human protransglutaminase 3 enzymes require calcium-regulated activation for their role in later stages of cell envelope formation in the epidermis and hair follicle.
3 citations
,
January 2021 in “ScienceAsia” In this study, combined treatment with transglutaminase and keratin significantly repaired damaged hair by improving its structural properties, reducing swelling, and enhancing crosslink activities, as evidenced by microscopy and spectroscopy analyses.
36 citations
,
June 1988 in “Australian Journal of Biological Sciences” This study found that twice-daily intradermal injections of mouse epidermal growth factor in Merino sheep resulted in dose-dependent changes in wool follicles and fibres, including induction of catagen and subsequent regeneration.
December 2022 in “Proceeding Bengkulu International Conference on Health” This study concluded that a 5% concentration of celery extract in hair gel provided the best preparation characteristics, including standard parameters for organoleptic properties and spreadability.
40 citations
,
February 1994 in “Journal of Investigative Dermatology”
10 citations
,
February 2023 in “Colloids and surfaces. A, Physicochemical and engineering aspects” This study found that a wound dressing made from egg white proteins, polyvinyl alcohol, and 1 mg/ml graphene oxide was most effective in promoting skin wound healing and tissue regeneration.
7 citations
,
January 1997 in “Bioscience Biotechnology and Biochemistry” This study found that both types of sheep hair follicle transglutaminases were calcium-dependent, contradicting earlier reports of calcium independence in this enzyme.
15 citations
,
February 2009 in “Cell Stem Cell” This study found that hair germ cells, derived from bulge stem cells, respond faster to dermal papilla signals and have limited proliferation compared to bulge cells during hair regeneration.
December 2025 in “Revista em Agronegócio e Meio Ambiente” This study investigated the effects of ultrasound-assisted extraction on sunflower seed oil mixed with defective green coffee grains, finding that higher coffee grain ratios decreased oil yield but increased phenolic content and antioxidant activity, with potential applications for wound treatment.
25 citations
,
April 2019 in “Animals” In this study, KRTAP28-1 variants were associated with wool fibre diameter in sheep, suggesting potential as a gene marker for reducing fibre diameter.
4 citations
,
January 2024 in “Scientific Reports” Pumpkin seeds may help expel parasites, but findings are retracted.
September 2024 in “Genes” This study found significant genetic differences between pigs with and without hair whorls, suggesting potential implications for pig breeding strategies in China.
3 citations
,
April 2002 in “Animal Science” This study found that intradermal spermidine injections stimulated cell proliferation and increased fibre length growth rate in wool follicles of Merino lambs, without significantly affecting fibre diameter.
53 citations
,
July 2021 in “International Journal of Molecular Sciences” This study found that extracts from Geranium pyrenaicum show promising antioxidant, enzyme inhibitory, and antiviral activities, particularly the methanolic extract's antiviral activity against HSV-1.
April 2018 in “Journal of Investigative Dermatology” This study found that a water-soluble peptide from chicken egg yolk, named Hair Growth Peptide, improved hair growth in mice and female pattern hair loss through increased IGF-1 and VEGF production.
5 citations
,
June 2015 in “Chinese journal of natural medicines/Zhongguo tianran yaowu/Chinese Journal of Natural Medicines” This study found that Tripterygium wilfordii multiglycoside significantly inhibited testosterone-induced benign prostatic hyperplasia in rats without causing toxicity, suggesting its potential as a therapy for BPH.
April 2025 in “Drug Design Development and Therapy” This study observed that the herbal extract WJWE promoted hair growth and protected hair follicle cells in a DHT-induced murine model of androgenetic alopecia, potentially by engaging the SIRT1/JNK/p38 MAPK and Wnt5A/β-Catenin signaling pathways.
23 citations
,
January 2021 in “Scientific Reports” In this study, hair follicle germs containing vascular endothelial cells showed improved hair regeneration and morphogenesis-related gene expression in mice, suggesting a promising strategy for hair regenerative medicine.
8 citations
,
February 2005 in “International Journal of Cosmetic Science” The study found that applying Bifidobacterium-fermented soy milk extract to human skin significantly reduced the decline in skin elasticity, suggesting its potential as a cosmetic ingredient to prevent skin aging.
4 citations
,
February 2018 in “Jurnal teknologi” This study found that Kaempferia galanga ethanolic extract has potential as an antifungal agent in an oil-in-water cream formulation, exhibiting stable physicochemical properties in laboratory tests.
2 citations
,
January 1994 in “Nihon Chikusan Gakkaiho” In this research, Holstein cows immunized with human hair keratin produced antibodies in both colostrum and regular milk that specifically bind to hair keratin, enhancing hair tensile strength without affecting skin keratin.
4 citations
,
January 2022 in “SSRN Electronic Journal” This study presents a novel, scalable method for preparing highly hair-inductive tissue grafts using a bioprinter, which enhances hair follicle regeneration in mice, although most hair shafts remained beneath the skin.
30 citations
,
December 2014 in “BMC Genetics” This study found thousands of differentially expressed genes and proteins that may be associated with wool growth, suggesting potential gene families involved in hair growth regulation.
January 2024 in “ACS Biomaterials Science & Engineering” In this study, researchers developed a microfluidics-based method to generate hair follicle germs on a large scale for potential hair regeneration therapies, demonstrating efficient hair follicle regeneration following transplantation into mice.
22 citations
,
September 1982 in “Journal of ultrastructure research” This study reports new cellular features and complex interaction systems in fiber differentiation, indicating more intricate cellular organization than previously recognized, including features like mast cells and primary cilia.
11 citations
,
January 2018 in “Acta dermato-venereologica” In this study, researchers identified gremilin-2 as a highly specific gene to the dermal sheath cup, suggesting it plays a key role in maintaining its properties.
7 citations
,
January 2025 in “ACS Applied Materials & Interfaces” This study developed a zinc-infused egg white and GelMA hydrogel that enhanced cellular processes crucial for wound healing, including fibroblast proliferation and collagen expression, and demonstrated promising biocompatibility and bioactivity in vivo, suggesting potential effectiveness in repairing damaged tissues.
13 citations
,
January 2015 in “Evidence-based Complementary and Alternative Medicine” This study found that ethanol extracts of Allium tuberosum Rottler ex Spreng significantly promoted hair growth in mice, possibly by increasing IGF-1 expression.
16 citations
,
June 2022 in “Acta biomaterialia” This study presents a bioprinter-based method for creating scalable, automated hair-inductive tissue grafts that showed improved hair shaft sprouting in mice by using suture guides to control orientation.
1 citations
,
February 2023 in “International journal of research - granthaalayah” This study reports that electromagnetic energy from a hydrocolloid wound dressing paste adversely affected human skin lipid droplets in vitro, but the implications, including potential cancer links, are unknown.