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The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

LGBT individuals have unique skin health needs, including higher STD risks and side effects from gender-affirming treatments, requiring dermatologists to offer knowledgeable and culturally competent care.

Certain skin conditions may indicate or increase the risk of Parkinson's disease.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Surface-modified nanoparticles mainly use non-follicular pathways to enhance skin permeation of ibuprofen and could improve treatment for inflammatory skin diseases.

Ludwig pattern hair loss in women results from varying sensitivity in hair follicles, causing fewer visible hairs.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

People with hair loss conditions experience more anxiety, depression, and a lower quality of life than those without these conditions.

New genes found linked to balding, may help develop future treatments.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Dendrobium officinale polysaccharides may help with hair growth, skin moisturization, and protection against oxidative damage.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Plasmacytoid dendritic cells are a key factor in causing hair loss in alopecia areata and could help differentiate it from other hair loss conditions.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

High levels of androgens during early development may cause PCOS-like symptoms.

Thyroid hormone affects skin health, with too little causing rough, pale skin and too much leading to smooth, thin skin, and may also impact wound healing and skin conditions.

Skin cell clumping for hair growth is improved by a protein called fibronectin, which helps cells stick and move better.

Targeted cancer therapies have a significant but lower risk of causing hair loss compared to chemotherapy.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

TGF-β2 plays a key role in human hair growth and development.

A hair wrapped tightly around an infant's toe caused severe damage, requiring early removal and possibly surgery to prevent worse outcomes like amputation.

Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.

Women with PCOS are more likely to have insulin resistance and obesity, especially those with the most severe type I PCOS.

Damaging mitochondrial DNA in mice speeds up aging due to increased reactive oxygen species, not through the p53/p21 pathway.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.