December 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Stress can cause a type of hair loss in mice lacking the CCHCR1 gene.
Sinsun-yukza-hwan extract promotes hair growth in mice.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Both induced and spontaneous AA lymphocytes can cause alopecia areata in mice.
Tissue from dog stem cells helped grow hair in mice.
108 citations,
July 2002 in “Molecular and cellular biology” Overexpressing Dsg3 in mice skin causes excessive cell growth and abnormal skin development.
75 citations,
March 2014 in “Journal of Investigative Dermatology” Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.
57 citations,
June 2003 in “American Journal of Physiology-cell Physiology” Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.
53 citations,
November 2006 in “Journal of Endocrinology” Prolactin slows down hair growth in mice.
34 citations,
November 2011 in “Alcoholism: Clinical and Experimental Research” Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
30 citations,
August 2016 in “Advances in radiation oncology” Researchers developed a mouse model that successfully mimics the bladder damage seen in humans after radiation therapy.
22 citations,
February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
22 citations,
October 2012 in “Cell Transplantation” Cells treated with Wnt-10b can grow hair after being transplanted into mice.
21 citations,
July 2020 in “Stem Cell Research & Therapy” Fat stem cells from diabetic mice can still help heal wounds.
20 citations,
September 2010 in “Cell Cycle” Mice can regenerate ear tissue without the p53 protein.
19 citations,
January 2013 in “International journal of medical sciences” Increasing Wnt5a in mice skin delays hair growth but doesn't stop it.
19 citations,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
17 citations,
February 2015 in “Cell Death and Disease” Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.
17 citations,
May 2003 in “Journal of The American Academy of Dermatology” Hair from balding and non-balding areas regrows similarly on mice.
14 citations,
March 1995 in “Journal of cell science” SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
13 citations,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
11 citations,
December 2014 in “The American journal of pathology” A gene deletion in mice causes weak protein, immune issues, hair loss, airway problems, and wasting disease.
8 citations,
March 2014 in “American Journal of Pathology” Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
8 citations,
January 2007 in “International journal of experimental pathology” Hairless HRS/J mice resist Bacillus anthracis skin infections due to high numbers of immune cells, not because they lack hair follicles.
4 citations,
October 2009 in “Skin research and technology” Colorimetry can accurately measure hair growth rates in mice.
January 2017 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” Mice with a changed Hr gene lose and regrow hair due to changes in the gene's activity.
December 2023 in “Biological & pharmaceutical bulletin” IPM enhances skin penetration of hydrophilic drugs.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
688 citations,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
218 citations,
October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.
194 citations,
March 2003 in “American Journal of Pathology” Stress stops hair growth in mice by causing early hair growth phase end and harmful inflammation through a specific nerve-related pathway.