In a case report, this study identified a new genetic variant in a six-year-old girl from Saudi Arabia with hypotrichosis and juvenile macular dystrophy, expanding the understanding of the genetic spectrum of this rare condition in the region.
March 2007 in “Journal of Cell Science” This study found that keratin K1014chim expression in mice did not reduce epidermal cell proliferation but increased susceptibility to benign tumors, challenging previous beliefs about K10's role in inhibiting tumor development.
8 citations
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December 2003 in “Experimental Dermatology” In this study, injecting chimeric RNA–DNA oligonucleotides into mice skin caused a temporary mutation in keratin 17, altering hair morphology, but the mutation was transient due to genetic compensation or cell replacement.
March 1985 in “Journal of the American Academy of Dermatology” This research found that topical minoxidil may promote hair regrowth in alopecia areata by stimulating hair follicle epithelium and suppressing certain immune responses, with potential contributions from its vasodilatory effects.
54 citations
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January 2007 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that hair follicle homeostasis in mice requires vitamin D receptor expression in keratinocytes, independent of its ligand activation.
181 citations
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January 2009 in “Nature Genetics” In this study, researchers linked defects in U2HR, an inhibitory region in the HR gene, to Marie Unna hereditary hypotrichosis, suggesting a mechanism for controlling hair growth and addressing hair loss.
July 2025 in “Journal of Ayurveda and Holistic medicine.” In this study, researchers reported significant improvements in hair follicle diameter, thickness, and reduced hair root gap after treating male pattern hair loss with a regimen of Prachanna, Chitrakadi lepa, and Jeevamrutham lehyam over four months.
15 citations
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November 2012 in “Archives of Ophthalmology” This description of dystrophy hypotrichosis associated with juvenile macular dystrophy provides an overview of this rare disorder characterized by short hair from birth and progressive loss of central vision but reports no new findings.
August 2015 in “MOJ proteomics & bioinformatics” This study suggests that epithelial-derived pop-up keratinocytes (ePUKs) may improve regenerative medicine applications due to their specific phenotype and increased expression of proteins involved in regulating cellular movement and wound healing.
29 citations
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January 2003 in “KARGER eBooks” In this study, researchers concluded that hereditary 1,25-dihydroxyvitamin D-resistant rickets, characterized by specific mutations in the vitamin D receptor gene, may resolve metabolic abnormalities with age, though associated alopecia remains.
July 2019 in “Dermatologic Surgery” This abstract provides contact information for François Kuonen at the Lausanne University Hospital Center and reports no new research findings.
2 citations
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October 2019 in “Dermatologic Therapy” This study suggests using a handheld dermatoscope may allow for simple and efficient differentiation of eruptive vellus hair cysts by detecting vellus hair shafts, as demonstrated in a familial case involving five women.
4 citations
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August 2024 in “Journal of Cosmetic Dermatology” This study reports that injecting a non-cross-linked hyaluronic acid compound into keratosis pilaris-affected skin led to significant improvements in roughness, redness, and overall skin condition, while maintaining a favorable safety profile, making it a promising alternative treatment option.
26 citations
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February 1998 in “DNA and Cell Biology” This research identified that the constitutive and inducible expression of the Keratin 6 gene in transgenic mice skin is controlled by multiple regulatory elements spread throughout its 5' flanking region.
110 citations
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August 2004 in “British Journal of Dermatology” In this study, researchers identified the ventral matrix as the primary source of nail plate formation, while the dorsal portion is generated by the apical matrix.
May 2016 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that vertex accentuation is the second most common pattern of female pattern hair loss in Asian women, following the diffuse type.
This study identified skin pallor, xerosis, and various hair, nail, and oral manifestations as common in children with CKD compared to healthy controls.
13 citations
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May 2001 in “Current problems in dermatology” Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
April 2018 in “Dermatologic Surgery” This overview highlights the Dermatologic Surgery journal's detailed coverage of cosmetic and reconstructive skin surgery, but it reports no new research findings.
9 citations
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November 2023 in “Supportive Care in Cancer” This study found that breast cancer patients treated with CDK4/6 inhibitors plus endocrine therapy experienced more pronounced vertex hair loss and were less responsive to minoxidil treatment compared to those on endocrine monotherapy.
51 citations
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January 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel keratin-associated protein, KAP24.1, which is specifically expressed in the human scalp and located in the hair cuticle.
19 citations
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April 2021 in “Stem Cell Research & Therapy” This study found that transplantation of autologous stromal vascular fraction cells increased skin thickness and improved regeneration when combined with mechanical stretching, without severe adverse events.
May 2006 in “The Journal of Cell Biology” In this study, researchers at Johns Hopkins University found that Keratin 17 plays a signaling role in cell growth during a wound response by aiding mTOR pathway activation, beyond its structural functions.
January 2023 in “Skin appendage disorders” The case study reports a patient with acute telogen effluvium in the donor region post-hair transplant, highlighting trichoscopic findings that aid in diagnosis and reassuring the self-resolutive nature of this condition.
August 2024 in “Dermatology and Therapy” This report describes a case where a 44-year-old male treated with vorasidenib for diffuse low-grade gliomas developed unexpected hair growth, including in areas of severe hair loss, after one month, highlighting a previously undocumented side effect.
13 citations
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March 1997 in “Research in Veterinary Science/Research in veterinary science” This study found that epithelial keratin K 6 is associated with hyperkeratotic and ulcerated changes in the gastric pars oesophagea of pigs, suggesting epithelial proliferation plays a role in ulcer development.
22 citations
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January 2009 in “Medical mycology” In this case report, researchers identified Arthroderma vanbreuseghemii as the cause of a familial fungal infection, which was successfully treated with itraconazole and topical terbinafine cream.
82 citations
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March 1992 in “Journal of Investigative Dermatology”
January 2024 in “Indian Journal of Plastic Surgery/Indian journal of plastic surgery” This case report describes a flap advancement technique following skin expansion as a successful method to address primary essential cutis verticis gyrata, preserving hair growth and improving cosmetic outcomes.