March 2024 in “Portuguese Journal of Dermatology and Venereology” This study found that individuals with hair loss, particularly females, had significantly lower levels of serum ferritin, vitamin D, and vitamin B12 compared to controls, suggesting these deficiencies, especially vitamin D, may play a role in hair loss such as telogen effluvium.
1 citations
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April 2021 in “International Journal of Research in Dermatology” This study found low serum ferritin and vitamin B12 levels in a significant portion of women with chronic telogen effluvium, while vitamin D deficiency was less common.
163 citations
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October 2001 in “EMBO journal” This study found that endogenous activin plays a crucial role in wound healing and scar formation, as its inhibition led to delayed wound healing and reduced scar size in transgenic mice.
August 2018 in “Journal of The American Academy of Dermatology” Patients with multiple superficial venous thrombosis are at greater risk for serious complications like cancer and recurrent blood clots.
April 2018 in “Journal of Investigative Dermatology” The researchers reported that nicotinic acid normalized excessive sebaceous lipogenesis without affecting basal lipogenesis and suggested potential anti-acne benefits.
May 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study identified interactions between Vitamin D and Msx1 regulation pathways, noting that Msx1 overexpression decreases Vitamin D receptor expression in odontoblastic cells.
June 2006 in “Annales de Dermatologie et de Vénéréologie” This review highlights the potential benefits of spironolactone in dermatology, particularly for female acne, supporting its safety over long-term use without extensive testing, but presents no new clinical results.
13 citations
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December 2005 in “Traffic” In this study, researchers found that syntaxin 9, a novel syntaxin family member, interacts specifically with the epidermal growth factor receptor and may influence its transport and signaling in some epithelial cells.
12 citations
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September 2017 in “JDR Clinical & Translational Research” In this study, researchers observed that the success of treating hereditary vitamin D–resistant rickets in children depends on the mutation location in the VDR gene, notably with favorable dental development outcomes for those with the p.R391S mutation, despite persistent alopecia.
57 citations
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April 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that the vitamin D receptor is crucial for initiating the postnatal hair follicular cycle in mice, preventing alopecia associated with its inactivation.
114 citations
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June 2000 in “Endocrinology” In this study, the researchers found that alopecia in VDR null mice is likely due to issues with hair cycle initiation rather than defects in keratinocyte proliferation or differentiation.
1 citations
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March 2015 in “PubMed” This review discusses the role of vitamin D and its receptor in maintaining skin and hair follicle health, but it reports no new clinical findings.
34 citations
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April 2001 in “PubMed” This study found that eflornithine HCl 13.9% cream reduces unwanted facial hair growth in women, with effects seen in up to 60% of participants over 4-8 weeks, with mostly minor skin irritation reported.
January 2015 in “D-Scholarship@Pitt (University of Pittsburgh)” This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.
3 citations
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July 1992 in “Clinics in Dermatology” This article reviews the role of vitamin D and its metabolites in regulating calcium homeostasis and highlights their effects on the intestine, kidney, bone, and parathyroid gland, without reporting new clinical results.
1 citations
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May 2016 in “Journal of Cosmetic Dermatology” This study found that the expression of CK 15 and CK 19 in vitiligo patients undergoing phototherapy was correlated with improved repigmentation, suggesting their potential as markers for stem cell stimulation.
45 citations
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October 2018 in “JCI Insight” In a preclinical mouse model, this study found that early treatment with the selective SYK inhibitor entospletinib significantly improved survival rates and clinical outcomes for graft-versus-host disease after hematopoietic stem cell transplantation compared to placebo.
June 2026 in “Advanced Healthcare Materials” This study found that engineered extracellular vesicles (293F-EGF-EV), enriched in EGF mRNA, significantly aided skin wound healing in vitro and in a rat model by promoting fibroblast activity and improving wound recovery through processes like angiogenesis and reduced scarring.
1 citations
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August 2012 in “Pediatrics in review” This paper reviews various vitamin deficiencies, including vitamin D, and highlights their potential health impacts. It does not report new research findings but discusses current recommendations and risks associated with these deficiencies.
51 citations
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January 2024 in “Burns & Trauma” This review summarizes the therapeutic potential and development of engineered extracellular vesicles for tissue repair and regenerative medicine, reporting no new clinical findings.
3 citations
,
January 2025 in “SAGE Open Medical Case Reports” In this case report, a 48-year-old woman with refractory discoid lupus erythematosus showed significant improvement, including hair regrowth, after treatment with deucravacitinib, suggesting its potential as an effective therapy for this condition.
37 citations
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June 2017 in “Journal of Investigative Dermatology” This study suggests that the interaction between CXXC5 and Dishevelled is a potential target for promoting hair regrowth and hair follicle formation, offering a new approach to treat hair loss.
August 2019 in “Journal of The American Academy of Dermatology” RV3466F lotion significantly reduces hair loss and improves acute telogen effluvium.
26 citations
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February 1978 in “Journal of Pediatric Surgery” This study found that long-term total parenteral nutrition in pediatric patients led to severe zinc deficiency, which improved with intravenous zinc therapy, highlighting the need for adequate zinc inclusion in nutritional solutions.
September 2019 in “Journal of Investigative Dermatology” This study demonstrated that an RO formulation significantly improved neck wrinkles after 8 weeks of application, compared to a placebo, in Japanese female subjects.
June 2026 in “Journal of Investigative Dermatology” This study found that certain proteins linked to immune suppression and melanogenesis are associated with repigmentation in vitiligo patients undergoing standard treatment, suggesting these proteins and their pathways play roles distinct from merely reversing skin lesions.
June 2026 in “Scientific Reports” This study found that nestin-expressing hair follicle-derived cells express higher levels of certain neurotrophic factors and neural markers, indicating potential for neuroregenerative therapy applications.
21 citations
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June 2022 in “Pharmaceutics” This study found that bioactive extracts from goat placenta, particularly when delivered via dissolving microneedles, enhanced fibroblast proliferation and skin regeneration without being toxic to skin cells, suggesting a promising dermal application for improving skin health.
January 1990 in “대한피부과학회지” This study found that peanut agglutinin binding patterns after neuraminidase pretreatment can help differentiate malignant melanoma from nevocellular nevus in skin specimens.
January 2006 in “Linchuang pifuke zazhi” This study found that stem cell factor combined with fibronectin and type IV collagen promotes migration of amelanotic melanocytes, which may help explain their movement during vitiligo repigmentation.