Clinical Characteristics and Outcomes of Patients with Superficial Venous Thrombosis at Multiple Sites Simultaneously

    Rishi Chopra, Luis de León, Nicos Labropoulos
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    TLDR Patients with multiple superficial venous thrombosis are at greater risk for serious complications like cancer and recurrent blood clots.
    The document presents a study that investigated the clinical characteristics and outcomes of patients with multiple simultaneous superficial venous thrombosis (SVT), a condition where a blood clot forms in a superficial vein, often accompanied by inflammation. The study aimed to determine if patients with multiple, unprovoked SVTs are at higher risk for thrombophilia, cancer, recurrent venous thromboembolic (VTE) events, or death. Twenty-four patients with multiple unprovoked SVTs were enrolled, and they underwent blood tests, CT scans, and follow-up examinations for at least 3 months. The results showed that 20.8% of the patients had cancer, 41.7% had thrombophilia, 29.2% experienced recurrent VTEs, and 16.2% died during the follow-up period. Patients with coexisting thrombophilia or cancer had a higher thrombotic load and increased VTE recurrence compared to those without such conditions. The study concluded that patients with multiple SVTs are at greater risk for serious complications and that further research with a larger multicenter design is warranted. No commercial support was identified for this study.
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