Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this study, 17β-estradiol increased VEGF production in differentiated THP-1 cells, while dihydrotestosterone counteracted this effect by modulating adenylate cyclase activity.

This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.

This review summarizes that polyesters hold promise for vascular tissue engineering due to their mechanical properties and biodegradability, but optimizing their use in repairing damaged blood vessels remains challenging due to the complexity of vascular tissues.

This study reviewed the prospects and challenges of using stem cells from adipose tissue in regenerative medicine for facial rejuvenation, emphasizing the need for further research to ensure patient safety before these methods can become routine in cosmetic and reconstructive surgery.

This study shows that ZIP7 is a functional zinc transporter in mammalian cells, facilitating the movement of zinc from the Golgi apparatus to the cytoplasm.

This review examines the evolving understanding of lymphatic vessel development, emphasizing new cellular mechanisms and lineage diversity, while discussing experimental methods and identifying key knowledge gaps.

In this study, researchers observed that in a limb ischemia model, vascular transplants preserved for 3 days had better recovery from ischemia-reperfusion injury compared to those preserved for 7 days, with less tissue edema and necrosis.

This study highlights that while advances in dermatology, such as biologics and JAK inhibitors, have improved treatments for conditions like atopic dermatitis and psoriasis, challenges remain, including issues with lasting efficacy and the need for more personalized therapies.

This dissertation investigated barriers to clinical translation of adipose-derived mesenchymal stem cell-based vascular grafts, highlighting issues with thrombosis in diabetic patients and proposing alternative cell sources to improve applicability.

In this study, mycorrhizal fungal inoculation was associated with increased root-hair growth and enhanced drought tolerance in trifoliate orange by modulating auxin synthesis and transport under water stress conditions.

This study found that PEGylated LUT-Aspasomes significantly improved neuroprotective effects in stressed rats, enhancing spatial memory, reducing depressive-like behavior, and preserving hippocampal architecture better than free luteolin. Additionally, it increased brain delivery and stability, suggesting potential for treating stress-related neurobehavioral disorders.

This study reported the development of fluorescent markers using wide band gap metal oxides with rare earth ions for early tumor detection and treatment. Testing in animals showed high efficiency and selectivity, with potential applications in contrast-enhanced MRI, targeted drug delivery, and photodynamic cancer therapy.

This study found that estradiol and other sex steroids reduced the capture of monocytes by human endothelial cells in vitro, potentially inhibiting the formation of atherosclerosis by promoting nCAM polysialylation, which interferes with leukocyte tethering to the vascular endothelium.

This study suggests that extracellular vesicles from prostate cancer cells could aid in identifying tumor heterogeneity and serve as biomarkers, while also playing a role in SARS-CoV-2 infection in nasopharyngeal mucus.

This study found that age-related changes in scalp dermal fibroblasts, including increased MMP-1 and reduced ECM components, may significantly affect the hair follicle environment and contribute to hair aging.

This study reports that beta-glucan hybrid hydrogels, reinforced with laponite nanoclay, showed promising results in rat models for managing hemorrhage and diabetic wound healing by enhancing hemostasis, reducing inflammation, and promoting faster wound closure and tissue regeneration.

This review highlights recent advancements in using niosomes as nanocarriers for improved delivery and sustained release of active cosmetic compounds, discussing their properties, applications, and future potential in cosmetic chemistry.

In this study, sildenafil was found to enhance human dermal papilla cell proliferation and promote hair growth in mice, suggesting potential use in alopecia treatment.

In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.

This study found that FZD2 is crucial for hair follicle formation and postnatal growth in mice and has a novel role in regulating early epidermal development, including stratification and cornification.

In this study, researchers developed a 3D-printed vascular model to analyze how different shear stresses influence cell behavior and promote cellular organization around neovessels, offering insights into tissue engineering for wound reconstruction.

This study found that VEGF significantly enhances perifollicular vascularization during the hair growth phase, accelerating hair regrowth and increasing follicle and hair size, while its inhibition retards hair growth.

This study found that thrombospondin-1 plays a critical role in hair follicle cycle regulation, with deficiency prolonging follicle growth and overexpression delaying it through antiangiogenic effects.

This review discusses the use of platelet lysate and its growth factors in treating diseases and regenerative medicine but reports no new clinical findings.

This review discusses the skin side effects associated with targeted cancer therapies and reports no new clinical results; it emphasizes the need for empirical management based on expert opinion.

This article discusses the range of skin-related side effects caused by chemotherapy and radiotherapy, including novel patterns emerging with targeted therapies, but does not report new clinical results.

This review proposes an anatomy-based framework for understanding recipient site scalp necrosis in hair transplantation, emphasizing regional vascular vulnerability and surgical factors, but does not provide new clinical results.

This review found that adipose-derived stem cells and stromal vascular fraction have robust clinical benefits in aesthetic surgery, particularly in facial rejuvenation, scar treatment, and volumetric restoration, with favorable safety profiles.

This review discusses the role of cholesterol homeostasis in hair follicle biology and its potential connections to various hair disorders, but it reports no new findings.

This study found that hucMSC-EXOs delivered via intratympanic injection effectively target vestibular sensory tissues, significantly reducing gentamicin-induced balance issues and high-frequency hearing loss, with some measured outcomes surpassing those achieved with dexamethasone.