Mesenchymal Stem Cell-Derived Exosomes Ameliorate Gentamicin-Induced Vestibular Hair Cell Injury by Regulating the SNARE Pathway and Enhancing Autophagy

    December 2025 in “ Stem Cell Research & Therapy
    Ruokang Han, Ning Yu, Guisheng Qi, Jing Wang, Yanan Wu, Chuan Qin, Lin Shi, Liang Wang
    New to Exosomes? There is a guide in the encyclopedia. Read the guide →
    Studysummary This study found that hucMSC-EXOs delivered via intratympanic injection effectively target vestibular sensory tissues, significantly reducing gentamicin-induced balance issues and high-frequency hearing loss, with some measured outcomes surpassing those achieved with dexamethasone.
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