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research Mesenchymal stem cell-derived exosomes ameliorate gentamicin-induced vestibular hair cell injury by regulating the SNARE pathway and enhancing autophagy

1 citations , December 2025 in “Stem Cell Research & Therapy”

This study found that hucMSC-EXOs delivered via intratympanic injection effectively target vestibular sensory tissues, significantly reducing gentamicin-induced balance issues and high-frequency hearing loss, with some measured outcomes surpassing those achieved with dexamethasone.

research Induction of autophagy improves skin and hair conditions in dogs with underlying diseases

1 citations , January 2023 in “Frontiers in veterinary science”

This study found that treatment with a synthesized autophagy inducer improved skin barrier function and hair damage in dogs with atopic dermatitis or hyperadrenocorticism by reducing pro-inflammatory cytokines.

Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter on Human Dermal Fibroblasts

research Air Pollution, Autophagy, and Skin Aging: Impact of Particulate Matter (PM10) on Human Dermal Fibroblasts

68 citations , September 2018 in “International Journal of Molecular Sciences”

In this study, researchers found that exposure to PM10 significantly increased inflammation and impaired collagen synthesis in human dermal fibroblasts, suggesting PM10 contributes to skin aging through these mechanisms.

research New multi-targeting strategy in hair growth promotion: in vitro and in vivo studies

3 citations , May 2018 in “Italian journal of dermatology and venereology”

In this study, using a lotion containing N1-methylspermidine and Sandalore® for 3 months significantly reduced hair loss and stimulated hair growth in both men and women with chronic telogen effluvium, with benefits persisting 3 months after treatment ended.

research Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6

6 citations , November 2023 in “Chinese Medicine”

This study found that Xinyang Tablet may improve cardiac function in LPS-induced sepsis-induced myocardial dysfunction by modulating macrophage polarization and autophagy through affecting LncSICRNT1 and TRAF6 expression.

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Community Join

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community Short Peptides for Hair Loss: anyone tried any of these?

14 upvotes 5 months ago

Various peptides are discussed for treating male pattern baldness, with some available for topical use like GHK-Cu and Ac-KGHK, while others remain in research stages. Users are interested in experiences and sourcing these treatments.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 3 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

community Pro as Heck Guide to Hairloss

48 upvotes 6 years ago

The conversation discusses a hair loss treatment protocol involving minoxidil, finasteride, ketoconazole shampoo, and RU58841. The user reports success with this regimen, particularly noting RU58841's effectiveness in regrowing hair without side effects.

community Nutrafol Women’s Balance vs Viviscal Pro?

2 upvotes 10 months ago

OP experienced thicker hair and less shedding with Nutrafol Women’s Balance but had flushing due to ingredients, and is considering switching to Viviscal Pro with saw palmetto. A user shared that Viviscal increased shedding for both him and his girlfriend, and suggested stopping Nutrafol if the hair loss is due to Telogen effluvium.

community I asked Gemini 2.5 Pro to roast r/tressless

in Satire 35 upvotes 1 year ago

Hair loss concerns and treatments like Minoxidil and Finasteride are humorously discussed. The community's quirks and dedication to battling hair loss are highlighted.

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