Stem Cell-Based Hair Cell Regeneration and Therapy in the Inner Ear

    October 2023 in “ Neuroscience Bulletin ”
    Jieyu Qi, Wenjuan Huang, Yicheng Lu … Renjie Chai
    Studysummary In this review, the authors discuss how understanding and co-regulating multiple signaling pathways could lead to effective regeneration of functional hair cells, highlighting current achievements and future approaches such as small molecule drugs and gene therapy for treating sensorineural hearing loss.
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    Research cited in this study 2

    1. Follistatin Promotes LIN28B-Mediated Supporting Cell Reprogramming and Hair Cell Regeneration in the Murine Cochlea Science Advances · 2022
    2. Chemical Screening for Hair Cell Loss and Protection in the Zebrafish Lateral Line Zebrafish · 2010