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      learn Follistatin

      glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin

      learn Metformin

      diabetes drug with anti-inflammatory, immunomodulatory, and insulin-sensitizing properties

      learn Finasteride

      Frontline, gold standard treatment for combatting androgenic alopecia

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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 11 months ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Second shed, non-stop flaking, itching

      in Treatment  12 upvotes 5 months ago
      The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.

      community Guide To Finasteride and Avoiding Side Effects

      in Finasteride/Dutasteride  23 upvotes 2 years ago
      The conversation provides a guide on using finasteride for hair loss, suggesting to start with a quarter of a 1mg pill daily after ensuring estradiol levels are within a specific range, and potentially increasing the dose if no side effects occur. It also recommends supplements like DIM, Calcium d-glucarate, and Zinc to manage high estradiol levels and side effects from finasteride.

      community Three years + or - on the Big 3. Plus Biotin.

      in Progress Pictures  665 upvotes 2 years ago
      The conversation discusses a user's hair regrowth over three years using Minoxidil, Finasteride, and a hair transplant, along with Biotin supplementation. Some users question the authenticity of the results and the organization of the before-and-after photos.