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Glossary Parkinson's disease

progressive neurodegenerative disorder affecting movement control due to dopamine loss

Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects movement control. It is characterized by symptoms such as tremors, stiffness, slowness of movement, and balance problems, resulting from the loss of dopamine-producing neurons in a region of the brain called the substantia nigra.

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Research

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research Parkinson's disease and skin

28 citations , January 2021 in “Parkinsonism & related disorders (Online)/Parkinsonism & related disorders”

This article reviews skin disorders in Parkinson's disease, highlighting the potential of skin studies and stem cell research to advance understanding and treatment of the neurodegenerative disorder, without presenting new results.

research Levodopa-induced skin disorders in patients with Parkinson disease: a systematic literature review approach

12 citations , July 2019 in “Acta Neurologica Belgica”

This review evaluated the evidence on skin disorders linked to levodopa treatment for Parkinson's disease, suggesting a possible association with melanoma, though evidence remains inconclusive and further studies are needed.

research Is seborrhea a sign of autonomic impairment in Parkinson's disease?

46 citations , November 1997 in “Journal of Neural Transmission”

Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.

research Telogen effluvium associated with the dopamine agonist pramipexole in a 55-year-old woman with Parkinson's disease

14 citations , October 2006 in “Journal of The American Academy of Dermatology”

This report highlights a case where a woman's use of the dopamine agonist pramipexole for Parkinson's disease was associated with hair loss, which improved after discontinuing the drug.

research Three-Dimensional Analysis of Sex- and Gonadal Status- Dependent Microglial Activation in a Mouse Model of Parkinson’s Disease

2 citations , January 2023 in “Pharmaceuticals”

This study found that in male mice, microglial changes due to a Parkinson's-like lesion were influenced by sex hormones, with dutasteride treatment preventing some effects.

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community Horrible news, Stemson Therapeutics has shut down

193 upvotes 1 year ago

Stemson Therapeutics has shut down, disappointing those seeking a hair loss cure. Current treatments like minoxidil, finasteride, and dutasteride are discussed, with some users experiencing side effects and exploring alternatives like PP405.

community If PP405 goes systemic this would be quite catastrophic

in Research/Science 4 upvotes 1 year ago

Concerns about the potential systemic effects and safety of PP405 for hair loss, with discussions on its comparison to existing treatments like finasteride and minoxidil. Users express skepticism about untested research chemicals and emphasize the importance of clinical trials to ensure safety and efficacy.

community Drinking minoxidil lands human in ICU with shock and heart failure

in Minoxidil 804 upvotes 2 years ago

A person mistakenly drank an entire bottle of topical minoxidil, leading to ICU admission with shock and heart failure. The incident highlights the dangers of ingesting topical treatments and the importance of proper usage and dosage.

community creatine has not effected my hair

22 upvotes 2 years ago

Creatine generally does not affect hair loss, but some report increased shedding due to higher DHT levels. Many manage hair loss with dutasteride, finasteride, and minoxidil.

community Federal Grant Cuts have impacted PP405 related research

459 upvotes 1 year ago

Federal funding cuts have delayed PP405 research, affecting hair loss treatment progress, though clinical trials will continue. The discussion highlights PP405's potential compared to minoxidil and finasteride and stresses the importance of government-funded research.

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