July 2026 in “European Urology Focus” This study found a significant association between baldness patterns, particularly vertex and early-onset baldness, and an increased risk of prostate cancer.
56 citations
,
June 2001 in “European journal of cardiovascular prevention & rehabilitation” This study found that men with early-onset androgenic alopecia have a higher risk of needing coronary revascularization before age 60 compared to those with later onset or no hair loss.
21 citations
,
November 2012 in “Plastic and Reconstructive Surgery” The researchers reported that various environmental factors and higher testosterone levels were linked to different patterns of hair loss in women with androgenic alopecia.
9 citations
,
July 2018 in “Medicine” This meta-analysis suggests that individuals with vertex baldness may have a higher risk of prostate cancer, though overall baldness is not significantly associated with prostate cancer risk.
8 citations
,
April 2001 in “Dermatologic Surgery” This proposal presents a standardized system for naming areas of the balding scalp to improve communication among hair restoration professionals, defining major regions and introducing new landmarks.
3 citations
,
December 2014 in “Journal of Clinical Oncology” This study observed that men with frontal and moderate vertex baldness between ages 40 and 50 had a higher risk of aggressive prostate cancer, suggesting a potential link between baldness pattern and cancer risk.
August 2023 in “Journal of Cosmetic Dermatology” This study found that combining minoxidil and spironolactone was more effective for hair density and severity of hair loss in women with androgenic alopecia compared to minoxidil and finasteride, with no serious adverse effects reported.
April 2023 in “Journal of Investigative Dermatology” This study reports distinctive clinical, trichoscopic, and histopathological features of fibrosing alopecia in a pattern distribution among Chinese patients, suggesting possible racial differences compared to previous studies primarily involving Caucasians.
January 2012 in “Elsevier eBooks” Hair transplantation is highly effective with careful technique and attention to patient needs.
5 citations
,
July 2016 in “Journal of Clinical Hypertension” This study found that hypertensive patients with severe androgenic alopecia exhibited impaired coronary microcirculation, suggesting they may face increased cardiovascular risk.
20 citations
,
January 2014 in “International Journal of Trichology” This study found that early onset androgenetic alopecia in young Asian Indian Gujarati men is independently associated with an increased risk of coronary artery disease.
126 citations
,
January 2010 in “British Journal of Dermatology” This study found that the prevalence of androgenetic alopecia in Chinese men and women was lower than in Caucasians and similar to that in Koreans.
37 citations
,
February 2017 in “Anais Brasileiros De Dermatologia” In this study, researchers found that the prevalence of androgenetic alopecia was higher in their sample compared to other studies in Asian and Caucasian populations, and it was linked with age-related severity.
153 citations
,
March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
11 citations
,
May 2009 in “Medical Hypotheses” This paper proposes a theory explaining how the normal anabolic effects of androgens lead to structural changes and hair follicle miniaturization, contributing to androgenic alopecia.
2 citations
,
August 2013 in “Facial Plastic Surgery Clinics of North America” This review discusses unique anatomical features and management strategies for crown alopecia but reports no new clinical findings, focusing instead on surgical techniques for natural-looking results and optimal density.
1 citations
,
July 2016 in “International Journal of Dermatology” This article discusses androgenetic alopecia in Amerindian Mapuche people from southern Chile and reports no new clinical findings.
March 2025 in “International Journal of Trichology” This case report describes the first observed instance of fibrosing alopecia in a pattern distribution in a child, suggesting the condition is not solely androgen dependent.
August 2023 in “Clinical, Cosmetic and Investigational Dermatology” In this study, the Hamilton-Norwood subtype of female pattern hair loss was associated with early onset and polycystic ovary syndrome, while the Ludwig pattern was more common overall.
165 citations
,
December 2002 in “Molecular and Cellular Endocrinology” This study found that finasteride improves scalp hair growth in men with male pattern hair loss by reducing scalp dihydrotestosterone levels, but it did not benefit postmenopausal women with female pattern hair loss.
157 citations
,
July 2001 in “British Journal of Dermatology” In this study, the prevalence of androgenetic alopecia among Korean men and women was found to be lower than in caucasians, with Korean men showing more frontal hairline preservation and a higher incidence of 'female pattern' hair thinning.
110 citations
,
July 2010 in “Journal of The American Academy of Dermatology” Hair loss linked to higher heart disease risk in both men and women.
103 citations
,
June 2007 in “Endocrinology and Metabolism Clinics of North America” This article discusses treatment options for androgenetic alopecia, noting that medical interventions like finasteride and minoxidil can halt and partially reverse hair loss in mild to moderate cases, especially when combined with surgery.
43 citations
,
July 2018 in “Journal of The European Academy of Dermatology and Venereology” This study found that a topical solution combining 0.25% finasteride with 3% minoxidil significantly improved hair growth, as measured by hair density, diameter, and global assessment, in men with androgenetic alopecia, compared to 3% minoxidil alone, over 24 weeks without systemic adverse effects reported.
30 citations
,
September 2017 in “Clinics in Dermatology” This review explores the relationship between androgenetic alopecia and metabolic syndrome, suggesting an association that supports considering cardiovascular risk assessments in patients with this type of hair loss.
7 citations
,
July 2018 in “Journal of Investigative Dermatology” This article reviews the genetic research on male androgenetic alopecia, highlighting that over 300 associated risk variants have been identified, with unclear mechanisms of action.
6 citations
,
October 2007 in “Medical Hypotheses” This article proposes that androgenic alopecia might be an evolutionary mechanism for reducing prostate cancer risk by enhancing UV absorption, rather than being a risk factor.
6 citations
,
December 2013 in “Journal of Cutaneous Pathology” This study found that the distribution of mast cell prostaglandin d-synthase in the scalp spatially aligns with the pattern of androgenetic alopecia, suggesting a programmed vulnerability to hair loss.
4 citations
,
August 2020 in “Journal of The American Academy of Dermatology” This review critiques a study on androgenetic alopecia in hospitalized COVID-19 patients, highlighting analytical inaccuracies and suggesting that the condition's prevalence may relate to older age rather than COVID-19 infection.
4 citations
,
April 2020 in “Journal of Cosmetic Dermatology” This study found that men with early androgenetic alopecia have a higher prevalence of hyperuricemia compared to those without the condition.