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Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.

The side gland of Suncus murinus is a good model for studying human sebaceous glands.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Flutamide rarely causes liver toxicity in prostate cancer patients.

The balance between androgen receptor and p53 is crucial for sebaceous gland differentiation.

Eclipta alba extract could be a promising natural treatment for hair loss.

The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.

The combined treatment of Finasteride and Doxazosin affects prostate tissue by reducing cell growth and altering hormone levels.

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

The main prostate diseases in dogs are benign growth, infections, and cancer, with various treatments ranging from drugs to surgery, but cancer treatments have limited success.

Finasteride affects prostate weights and pituitary activity differently with age.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

Finasteride effectively treats hair loss and enlarged prostate in men, with mild side effects.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.

New compounds can block testosterone effects in rats and might help treat conditions like prostate cancer and acne.

Antiandrogens like flutamide are effective in treating conditions like prostate cancer and hair loss, but there's a need for more potent versions. Understanding their structure can help develop better treatments.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Using two drugs together, Flutamide and 4-MA, is more effective for blocking male hormones than using each one alone.

Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.

Finasteride affects male rat genitalia development, causing abnormalities during specific pregnancy days.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Men with balding at age 45 had higher IGF-1 and lower IGFBP-3, suggesting these factors might be important in male pattern baldness.

Male hormones indirectly affect skin cell development by increasing growth factor levels from skin fibroblasts.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Men with balding at age 45 had higher IGF-1 and lower IGFBP-3 levels, suggesting these factors might influence male pattern baldness.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.