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Finasteride affects brain stress and enzyme activity differently in various regions, possibly helping with liver-related brain issues.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Testosterone changes important cell communication proteins in pregnant rats' uteruses, which might affect pregnancy success.

Finasteride helps treat skin issues like acne and baldness by blocking testosterone conversion.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

A plant extract was found to effectively block an enzyme related to male hormone-related diseases.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Finasteride effectively treats BPH but requires continuous use to maintain benefits.

Different enzymes are active in different parts of developing mouse organs.

Finasteride can cause sexual dysfunction and depression, which may persist and require hormonal treatment.

Tributyltin exposure causes sex changes, sterilization, and decline in the snail Ocinebrina aciculata, risking its extinction.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Using minoxidil on dogs can cause serious cardiovascular damage, including arterial injury and hemorrhagic lesions.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

Finasteride may cause mental and sexual side effects, with hand preference and sexual orientation possibly affecting severity.

FDG PET/CT scans can change cancer treatment plans for dogs.

Finasteride helps protect brain in old male rats.

Negative expectations can cause adverse effects in dermatology treatments, like with finasteride for baldness, and careful communication can help reduce these nocebo responses.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Testosterone and its metabolites affect brain functions and could help treat neurological disorders.

Urologists should monitor mental health in patients taking finasteride due to potential links to suicidal thoughts, adjusting dosage or stopping use if necessary. More research is needed to confirm if finasteride causes these thoughts.

Men and women react differently to opioids, with hormones potentially influencing these differences.

The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.

Finasteride metabolism varies by age, sex, and P450 inducers, with males processing it faster.

Some cats with sudden hair loss and tiredness might have cancer-related alopecia.

Finasteride affects young male rats' brain function and behavior negatively.

Schizophrenia risk genes may affect early brain development, contributing to the disease.