44 citations,
October 1989 in “International Journal of Pharmaceutics” Minoxidil's effectiveness decreases as vehicle evaporates; concentration and thermodynamic activity matter.
164 citations,
April 2008 in “Cochrane library” Current treatments for alopecia show no significant long-term benefits.
34 citations,
October 1994 in “Journal of Pharmaceutical Sciences” Ethanol over 50% helps minoxidil absorb better into skin.
62 citations,
May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
39 citations,
March 2009 in “Clinics in plastic surgery” Injection lipolysis effectively reduces small fat deposits and should be done with care and proper patient selection.
19 citations,
October 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” The gel made of minoxidil and hydroxypropyl-β-cyclodextrin improves hair growth and is good for long-term use.
39 citations,
April 2010 in “International Journal of Pharmaceutics” Nanoparticles improve minoxidil skin permeation, but more research needed for effective hair growth.
25 citations,
January 2013 in “Journal of Industrial and Engineering Chemistry” Some herbal extracts, especially when used in cubosomal suspensions, were as effective as Minoxidil in promoting hair growth.
38 citations,
March 2017 in “Expert Opinion on Investigational Drugs” Bimatoprost is promising for treating some types of hair loss but needs more testing for androgenetic alopecia.
3 citations,
June 1997 in “Veterinary Dermatology” Minoxidil treatment can stimulate hair growth in hairless puppies if applied early.
August 2023 in “Scientia Pharmaceutica” Color changes in Minoxidil hair products do not affect their effectiveness.
37 citations,
February 2010 in “Psychoneuroendocrinology” Androgen self-administration might be controlled by membrane receptors, not nuclear ones.
115 citations,
November 1999 in “Journal of The American Academy of Dermatology” Minoxidil increases hair weight and count temporarily in men with hair loss.
85 citations,
December 1990 in “Journal of Investigative Dermatology” Minoxidil promotes hair growth in women with early-stage alopecia.
5 citations,
January 1994 in “Skin Pharmacology and Physiology” Minoxidil absorption in skin is slowed by cleansing, depends on how long it stays on the skin, and is not much affected by reapplication.
104 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.
78 citations,
March 1987 in “Journal of The American Academy of Dermatology” Minoxidil promotes hair growth but stops working when discontinued.
24 citations,
September 2001 in “Journal of Dermatological Science” Cyclosporin A helps damaged hair follicles regrow hair quickly.
45 citations,
August 2011 in “Journal of Microencapsulation” Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
36 citations,
June 2001 in “Neuroscience Letters” Finasteride may affect fetal brain development and increase arousal, but more research is needed for safety confirmation.
13 citations,
September 2005 in “Eclética Química” Quick, accurate minoxidil measurement in hair loss products using photometric flow titration.
3 citations,
October 2014 in “Pharmaceutical Development and Technology” The study found a way to improve a skin-applied minoxidil formula using a specific design method.
16 citations,
December 2016 in “Skin appendage disorders” Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.
11 citations,
September 2020 in “Journal of Cosmetic Dermatology” Silver nanoparticles can significantly promote hair growth.
11 citations,
May 2010 in “Journal of Medicinal Chemistry” A new compound was created in 2010 that can control oil production when applied to the skin, and its effects are completely reversible after two weeks.
11 citations,
July 2008 in “European Journal of Drug Metabolism and Pharmacokinetics” Finasteride helps reduce pain and inflammation in animals.
6 citations,
January 2018 in “Journal of Cellular Physiology” Human scalp fat stem cells showed improved cartilage-like development on a special scaffold with freeze-thaw treatment.
January 2015 in “Elsevier eBooks” Nanocarriers like liposomes and cyclodextrins improve how angiotensin-(1-7) is delivered in the body.
316 citations,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
19 citations,
January 2016 in “Biological & Pharmaceutical Bulletin” Sargassum muticum extract and its component apo-9'-fucoxanthinone may help hair growth and treat hair loss.