In Vivo and In Vitro Hair Growth-Promoting Effect of Silver and Iron Nanoparticles Synthesized via Blumea Eriantha DC Plant Extract

The document from September 24, 2020, presents a study on the effects of silver and iron nanoparticles synthesized from Blumea eriantha DC plant extract on hair growth. The nanoparticles were characterized and had an average size of 35nm. The in vivo study involved Swiss Albino mice, divided into six groups of six animals each, and compared the effects of these nanoparticles with Minoxidil. Results indicated that 2% and 5% concentrations of silver nanoparticles induced 33.02% and 60.93% anagen hair follicle phase, respectively, while 2% and 5% iron nanoparticle treatments induced 44.09% and 38.89% anagen phase, respectively. The 5% silver nanoparticle treatment showed comparable results to Minoxidil in terms of hair growth initiation, length, weight, and anagen phase induction. The study concluded that silver nanoparticles, particularly at a 5% concentration, have a significant hair growth-promoting effect without causing skin irritation and could be a promising alternative to current treatments like Minoxidil and Finasteride. Further research is needed to understand the mechanism of action. The specific number of animals used in the study was not mentioned in the provided text.