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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Finasteride may cause long-lasting sexual side effects.

Folliculitis decalvans is a rare scalp condition causing scarring hair loss, treated with long-term antibiotics and other medications, but it often comes back and is hard to manage.

Minoxidil boosts hair growth by activating PGHS-1.

Neurosteroids show promise for treating epilepsy and more research is needed.

The peptide IMT-P8 can effectively deliver proteins into the skin and cells for potential skin treatments.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Certain skin conditions may indicate or increase the risk of Parkinson's disease.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Parkinson's disease is linked to skin disorders and skin cells help in studying the disease.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Finasteride can cause sexual problems and depression in young men.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

The enzymes 5α-reductase and 3α/β-hydroxysteroid oxidoreductase help create brain-active substances from progesterone and testosterone, which could be used for treatment, but more research is needed to ensure their safety and effectiveness.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

Lipid-coated silica nanoparticles penetrate human skin more deeply than bare silica nanoparticles.

Progesterone and its byproducts control a specific receptor in the brain independently of progesterone receptors, affecting conditions related to the menstrual cycle.

Minoxidil helps control blood pressure but has side-effects, so it's not for everyone.

Scalp involvement is common in pemphigus and can lead to hair loss, with the severity of scalp lesions linked to overall disease severity.

Pregnancy can cause various skin changes, including pigmentation, acne, and stretch marks, and may affect preexisting skin conditions.

Bacteria in our hair can affect its health and growth, and studying these bacteria could help us understand hair diseases better.

Hair loss can indicate or worsen with systemic diseases, and treating the underlying condition is important.

Rapamycin may help treat Leigh syndrome by targeting protein kinase C.

FLCN helps control iron levels in cells.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Early NAS level changes affect alcohol consumption vulnerability.

Skin changes throughout life, from development before birth to aging effects like wrinkles, influenced by both genetics and environment.