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This case study potentially links the use of anabolic steroids to increased severity of COVID-19 in a healthy 28-year-old man, with marked symptom improvement following treatment with proxalutamide.

In this study, Diane was reported to effectively treat acne, seborrhoea, androgenic alopecia, and mild hirsutism in hirsute women, with its effectiveness influenced by the severity and duration of the condition.

This research outlines a chemical synthesis process for Finasteride, detailing the conversion of pregnadienolone acetate through various chemical reactions and modifications.

This article reviews the current status of oral retinoids in dermatology and reports no new clinical findings.

This study demonstrated that a finasteride-loaded proniosome significantly enhanced transfollicular delivery and hair growth in mice without causing skin irritation, with effects comparable to a 2% minoxidil solution.

Hair loss can occur as a side effect of certain breast cancer treatments, but minoxidil can help regrow hair.

This in-silico study identified several compounds as potential Vitamin D Receptor agonists, with Dolichosterone showing the strongest binding energy.

This study found that among 17 beta-(N-ureylene-N,N'-disubstituted)-4-azasteroids, those with an N'-phenyl moiety were the most effective inhibitors of human type I 5 alpha-reductase.

This study found that a new formulation using short chain esters and ethanol can selectively deliver hydrogen peroxide to hair follicles during epilation, causing follicular damage without affecting epidermal keratinocytes.

This article outlines how nanotechnology strategies, including phospholipid-based nanocarriers like liposomes, could enhance the effectiveness and skin tolerability of acne treatments, aiming to reduce side effects and improve patient compliance in managing acne vulgaris.

This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.

This study found that both the natural ligand 1alpha,25(OH)(2)D(3) and the synthetic agonist LG190178 bind similarly to the vitamin D receptor's coregulator motifs, suggesting similar biological functions.

This research found that combining a 308-nm excimer laser with oral compound glycyrrhizin and topical 0.03% tacrolimus was more effective for treating pediatric facial and cervical vitiligo, resulting in faster and higher rates of repigmentation with minimal adverse effects compared to glycyrrhizin and tacrolimus alone.

This article reviews the role of liposomes in dermatology and does not report new clinical results.

In this review, researchers provided a comprehensive analysis of anti-androgen therapies for polyendocrine metabolic ovarian syndrome (PMOS/PCOS), examining their efficacy and safety while proposing a phenotype-guided management framework and highlighting research gaps, such as long-term cardiovascular safety and predictive biomarkers.

This study found that ethosomes containing 30% ethanol slightly improved the targeting of dutasteride to hair follicles in vitro, with a higher targeting factor compared to dried ethosomes and controls after 24 hours on porcine skin.

This study developed a polyherbal chocolate formulation aimed at managing PCOS and hormonal balance, finding that formulation F2 showed excellent organoleptic properties and stability, with future in vivo studies being suggested.

This study found that valproic acid may interfere with the leucine metabolic pathway by inhibiting 3-methylcrotonyl-CoA carboxylase and biotinidase, which could contribute to side effects like skin rash and hair loss in patients.

In this study, women treated for androgen-dependent alopecia with CPA EE2 therapy experienced significant decreases in serum vitamin B12, hemoglobin, and hematocrit levels after six months.

Two non-steroidal antiandrogens, RU 58841 and RU 56187, form a common metabolite at different rates, which may influence their effects; RU 56187 could be used for prostate cancer treatment and RU 58841 for acne treatment.

In this study, researchers reported that hardshell capsules using the DiluCap® line of excipients demonstrated varying dissolution profiles under gastrointestinal-simulating conditions, with minoxidil and finasteride showing rapid release and melatonin and naltrexone displaying controlled release, indicating their suitability for different applications in compounding pharmacies.

Custom software found that common allergy drugs might have new uses for various conditions and could improve survival in some cancers.

Clofazimine may be effective for treating ashy dermatosis.

This study observed that thyroid and hormone treatments did not resolve postpartum alopecia in a small patient group, and most cases may naturally revert to normal.

This study found that finasteride is stable under various stress conditions except for basic hydrolysis at extreme pH levels and identified compatible and incompatible excipients in pharmaceutical formulations, suggesting formulation changes for increased safety.

This study found that liposomes coated with cationic polymers, chitosan and Eudragit EPO, showed improved physicochemical stability and enhanced skin diffusion of aciclovir and minoxidil compared to uncoated liposomes.

In this study, the synthesis of C-4 and C-6 bridged haptens of 11 alpha-hydroxyprogesterone revealed an unexpected formation of a C-4 substituted product using a 6-bromo derivative, contrary to prior reports.

This article reviews the use of several medications for ovulation induction in polycystic ovary syndrome and hirsutism treatment, noting these uses are not FDA-approved; no new clinical results are provided.

This study found that 11α-hydroxyprogesterone is a potent inhibitor of 11βHSD2 in vitro and may serve as a precursor to unique C11α-hydroxy steroids in prostate cancer tissue.