14 citations
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May 2023 in “Dermatologic Surgery” VYC-12L effectively improves skin smoothness, reduces fine lines, and boosts hydration.
July 2020 in “Scholars journal of applied medical sciences” This study found that vomiting was the most common side effect of sodium valproate in children under two with epilepsy.
November 2025 in “American Journal of Case Reports” This case report describes a child with acrodermatitis enteropathica and normal zinc levels who developed Kaposi's varicelliform eruption, highlighting the role of novel SLC39A4 variants and the importance of early zinc supplementation and antiviral prophylaxis.
7 citations
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January 2016 in “Experimental and Clinical Endocrinology & Diabetes” This study observed that adding simvastatin to ongoing metformin treatment reduced certain androgen levels in women with non-classic congenital adrenal hyperplasia and abnormal glucose metabolism, suggesting a potential therapeutic benefit.
3 citations
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May 2010 in “Archives of dermatology” This excerpt discusses website navigation and access details for JAMA Dermatology and reports no new research findings.
January 2013 in “International journal of contemporary surgery” This study found that combining cyproterone acetate with topical eflornithine was a safe and effective treatment for facial hirsutism in women.
6 citations
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September 2010 in “Archives of Dermatology” This case study suggests that thermography could objectively assess pain severity in herpes zoster patients by correlating thermal images with reported pain intensity.
2 citations
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November 2015 in “Journal of Investigative Dermatology” This study found that RANKL signaling enhances CD8+ T cell-mediated anti-viral immunity during herpes simplex virus infection by preventing apoptosis of Langerhans cells, suggesting potential therapeutic applications.
1 citations
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September 2007 in “Neuromuscular disorders” This study suggests that long-term treatment with valproate, acetylcarnitine, folic acid, and vitamin B12 may benefit children with SMA types II and III by improving muscle strength and function without significant adverse effects.
14 citations
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November 2018 in “Journal of drug delivery and therapeutics” This article reviewed the preparation, application, and characterization of ethosomes as drug delivery transporters and reported that in a double-blind randomized clinical study, ethosomal acyclovir significantly improved all evaluated parameters in skin delivery, highlighting potential for novel therapies.
May 2022 in “Indian Journal of Pharmacology” This case report highlights a rare instance of valproate-induced hypertensive urgency in a 2-year-old girl, with improvement after stopping the medication.
13 citations
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January 2017 in “Annals of dermatology/Annals of Dermatology” In this study, simvastatin/ezetimibe treatment led to partial hair regrowth in about 29% of patients with recalcitrant alopecia areata, suggesting it may be a viable alternative therapy for this condition.
32 citations
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October 2004 in “Pharmacotherapy” In this study, peginterferon alfa-2b plus ribavirin therapy in hepatitis C patients was associated with serious adverse drug reactions in 20% of cases, highlighting differences from clinical trial findings.
16 citations
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November 2020 in “Research Square (Research Square)” In this study, early treatment with nitazoxanide, ivermectin, or hydroxychloroquine, combined with azithromycin, was associated with reduced hospitalizations, respiratory complications, and deaths in early-stage COVID-19 patients compared to untreated controls.
5 citations
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June 2019 in “JAAD Case Reports” This article discusses the use of imiquimod as a treatment for actinic keratosis, basal cell carcinoma, and human papillomavirus warts, noting both its therapeutic benefits and common side effects such as local inflammation and flu-like symptoms.
January 2016 in “International journal of clinical pediatrics” In this study, ultrastructural examination of hair in children treated with valproic acid showed a normal hair surface and cuticular pattern, despite reported hair changes with the drug.
November 2024 in “Journal of Cosmetic Dermatology” This study found that valproic acid-loaded microemulsion formulations enhanced skin penetration pathways in guinea pigs compared to an aqueous solution, with composition elements like oil content and surfactant ratios significantly affecting drug delivery performance.
1 citations
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January 2015 in “Annals of Dermatology” This case report describes a 52-year-old woman who developed retiform purpura after using cocaine likely adulterated with levamisole, highlighting the need for levamisole detection in such cases.
6 citations
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November 1999 in “Psychiatric services” This case report describes a woman who experienced complete but temporary scalp hair loss after a massive overdose of divalproex, suggesting a potential acute side effect of the drug.
70 citations
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July 2020 in “Pharmacological Reports” This review discusses the antiviral potential of cepharanthine against SARS-CoV-2, noting its effectiveness in preclinical models but presenting no new clinical results.
12 citations
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May 2005 in “Journal of the American Geriatrics Society” This case report describes successful treatment of valproate-induced hyperammonemia in a 79-year-old man using lactulose, marking the first such documented use for this condition.
4 citations
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October 2020 in “Actas Dermo-Sifiliográficas” This review examines the use of commonly used dermatological drugs like chloroquine, hydroxychloroquine, ivermectin, antiandrogens, and melatonin in COVID-19 treatment, but reports no new clinical findings.
1 citations
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January 2017 in “Journal of Clinical and Diagnostic Research” This case series reported three instances where alopecia linked to sodium valproate was reversed after discontinuing the drug.
1 citations
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October 2025 in “Frontiers in Immunology” In this study, researchers analyzed adverse events linked to avacopan using FDA data, finding no high-priority safety concerns but identifying five potential new adverse events, including alopecia, primarily among American patients, and noting a higher risk of liver dysfunction in Japanese patients.
1 citations
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January 2024 in “Sultan Qaboos University medical journal” In this study, mild adverse reactions to COVID-19 vaccines were reported among vaccinated staff and students, with females experiencing more reactions than males.
55 citations
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December 1983 in “Acta Neurologica Scandinavica” This review discusses the side effects of carbamazepine, valproate, and clonazepam, noting that these are rare with long-term use but more common, transient, and generally mild during early treatment.
February 2026 in “Libri Oncologici Croatian Journal of Oncology” The review found that imiquimod is a promising non-invasive treatment for HPV-related neoplasias, particularly effective for vulvar lesions, but notes that more research is needed to optimize its use.
June 1982 in “Revista Colombiana de Obstetricia y Ginecología” This article discusses treatments for androgenic manifestations using cyproterone acetate alone or with estrogens, but it does not provide new clinical results.
21 citations
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April 2011 in “Epilepsia” This open-label study suggests that combining valproate, lamotrigine, and a benzodiazepine can significantly reduce the frequency of epileptic drop attacks in patients with generalized or multifocal epilepsies.
19 citations
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April 2011 in “Headache The Journal of Head and Face Pain” This study found that both topiramate and divalproex sodium were similarly effective in reducing headache frequency by over 50% among episodic migraine patients after three months of treatment.