15 citations
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January 2019 in “Journal of the Formosan Medical Association” This case study reports that adding adalimumab to a 12-year-old VKH patient's treatment allowed for ocular inflammation remission, vision improvement, and corticosteroid tapering, suggesting escalation of immunosuppression may be critical in pediatric VKH cases.
December 2013 in “American journal of transplantation” This case report describes a 27-year-old kidney transplant recipient with end stage renal failure who developed infections and adverse reactions, ultimately resolving with antiviral treatment targeting HHV6.
October 2025 in “Influenza and Other Respiratory Viruses” This study found that bis-benzylisoquinoline and Amaryllidaceae alkaloids, especially aromoline, show potential as antiviral agents, suggesting they could serve as foundations for developing new treatments against coronaviruses by enhancing the understanding of their structure-activity relationships.
16 citations
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February 2009 in “Clinical neurology and neurosurgery” In this study, patients with epilepsy who switched from immediate-release to extended-release divalproex sodium did not experience significant changes in seizure frequency, but most preferred the new formulation due to a subjective decrease in tremor during daily activities.
5 citations
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December 2015 in “PubMed” This study identified several gonadal hormone drugs, including toremifene citrate, tamoxifen citrate, and clomiphene citrate, that effectively inhibited filovirus entry in a pseudovirus model.
20 citations
,
August 1981 in “Developmental Medicine & Child Neurology” 13 citations
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June 1981 in “Developmental Medicine & Child Neurology”
2 citations
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July 2023 in “Obstetrics & Gynecology” In this study, imiquimod was found to increase regression of cervical intraepithelial neoplasia compared to placebo, though it commonly caused side effects that rarely led to treatment discontinuation.
3 citations
,
October 1976 in “BMJ” In this case report, a 6-year-old boy developed thrombocytopenia while taking sodium valproate alone, after being seizure-free for eight months on the medication.
July 2017 in “Nursing2023” Actemra is approved for a specific artery condition, HIV treatment adherence has improved, women may pay more for a hair loss product, and incorrect dosing of blood thinners can be risky.
2 citations
,
September 2021 in “Human Psychopharmacology: Clinical and Experimental” This review discusses valproate-associated hair abnormalities, describing their common and benign nature, and outlines management strategies, though new clinical results are not provided.
28 citations
,
October 2000 in “International Journal of Dermatology” This case report details a 37-year-old man who developed eosinophilic pustular dermatosis after previously resolving herpes zoster, with successful treatment using itraconazole and cycloproxolamine.
1 citations
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October 2023 in “Journal of clinical psychopharmacology” In this case report, a young male developed bilateral pleural effusion and persistent fever after starting divalproex sodium for bipolar disorder, which improved upon discontinuation of the drug, suggesting a possible link between divalproex sodium and pleural effusion.
In this study conducted at Shafa Hospital, Kerman, Iran, 3.5% of patients using sodium valproate as an antiepileptic experienced hair loss and curling over ten years.
January 2026 in “Open Science Framework” This scoping review aims to map current knowledge about treatment strategies for alopecia caused by VPA (valproic acid) across various patient groups, identifying reported management strategies, supporting evidence, observed outcomes, and areas needing further research, but results are not provided.
1 citations
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September 1981 in “PubMed” This study found that treatment with cyproterone acetate was generally successful for women with virilizing features, showing improved results in younger women and those with adrenal hirsutism, despite some side effects.
17 citations
,
January 2013 in “Indian Journal of Pharmacology” This case report highlights an interest in exploring the relationship between serum levels of sodium valproate and hair loss, though no case reports currently establish this link.
15 citations
,
August 2002 in “British Journal of Ophthalmology” This paper discusses a case where intralesional cidofovir successfully treated squamous cell carcinoma without systemic toxicity, but surgical excision remains the standard for curative treatment and margin evaluation.
8 citations
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October 2019 in “The Journal of surgical research/Journal of surgical research” This study demonstrated that sodium valproate accelerates skin healing and reduces necrosis in a rat model of skin flap potentially through mechanisms involving GABA and histone deacetylase pathways.
6 citations
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March 2023 in “Frontiers in Cellular and Infection Microbiology” This study found that Golvatinib, Gliquidone, and Dihydroergotamine may inhibit the binding of SARS-CoV-2's Nsp1 protein to the host ribosomal subunit, suggesting potential as treatments against COVID-19 variants.
44 citations
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December 1975 in “Developmental Medicine & Child Neurology” This study found that sodium valproate effectively controlled petit mal seizures in children resistant to other anticonvulsants but was less effective for other seizure types.
1 citations
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January 2017 in “International journal of trichology” This case report suggests that topical diphenylcyclopropenone (DPCP) may be beneficial for treating both alopecia areata and verruca vulgaris, although it is not typically a first-line therapy.
1 citations
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November 2011 in “Journal of AIDS & Clinical Research” Raltegravir may cause hair loss in some patients.
This study found that sodium valproate improved seizure control in children with epilepsy, with increased weight gain being the most common side effect reported.
7 citations
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March 2018 in “Psychiatry and Clinical Psychopharmacology” This article presents five cases of valproate-induced hyperammonemic encephalopathy in psychiatric patients treated at the authors' clinic and discusses existing literature on this side effect.
May 2022 in “Gastroenterology” This study suggests that supplemental testosterone therapy in men with hepatitis C virus may be associated with a modest reduction in hepatocellular carcinoma risk, challenging concerns about its potential to increase cancer risk.
May 2011 in “Journal of Clinical Neuroscience” This article discusses a case of Vogt-Koyanagi-Harada disease, detailing symptoms, diagnostic features, and treatment with corticosteroids, but it reports no new clinical findings.
3 citations
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January 2000 in “Current Medical Research and Opinion” This research reported that eflornithine HCl 13.9% cream generally has a favorable dermal safety profile for managing unwanted facial hair in women, though it can cause mild irritation under certain conditions.
26 citations
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November 2016 in “European Journal of Clinical Pharmacology” This study found that using valproic acid during radiotherapy for glioma was associated with delayed hair loss and improved survival outcomes.
2 citations
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November 2011 in “Current psychiatry”