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Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively treats BPH, but needs more trials to understand potential.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Sebocytes play a key role in controlling androgen levels in human skin.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Hirsutism is more linked to high androgen levels than acne or hair loss, and a mix of hormonal tests is best for diagnosis; certain treatments can reduce symptoms.

Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Spironolactone most effective for hirsutism, but has side effects.

Eating fewer calories, less sugar and refined carbs, and more low-glycemic and omega-3 rich foods can help manage PCOS symptoms.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Effective hair loss treatment in women requires correct diagnosis and can include medications like minoxidil, antiandrogens, and treatments for underlying conditions like PCOS.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.

Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.

Finasteride effectively reduces hair loss by decreasing androgen levels.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

Genetics and hormones cause hair loss; finasteride treats it safely.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.