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Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Treating psoriasis on the scalp, nails, and skin folds is challenging, often requiring systemic treatments for severe cases, with some success in topical and biologic treatments.

Both vitiligo and alopecia areata involve an immune response triggered by stress and specific genes, with treatments targeting this pathway showing potential.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Hydrogen peroxide can cause scars by changing healing processes and increasing certain protein levels.

Dermatologists need to know about cosmetics to help patients with skin issues and recommend safe products.

Bimatoprost gel makes eyelashes grow longer, but may cause side effects and should be monitored by an eye doctor.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Obesity worsens Polycystic Ovary Syndrome symptoms, and weight loss is a key treatment.

We need better ways to test and understand SARMs to make safer and more effective treatments.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Deoxycholic acid effectively reduces double chin fat with temporary side effects and high patient satisfaction.

Older women reported negative physical and psychological effects from Botox and facial fillers, feeling neglected by the medical system.

Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.

All medications can cause skin rashes, often without a clear cause, and better tests are needed to identify these drug-related skin issues.

Common cosmetic dermatology techniques improve skin damaged by the sun and aging.

Hormone therapy is safe and effective for transgender adults, but requires regular monitoring and mental health support.

A compound from Calophyllum inophyllum L. leaf may help treat non-small cell lung cancer.

Excessive eyelash growth from erlotinib may indicate positive tumor response and help treat madarosis.

Nitroglycerin ointment is now used to treat several skin conditions with fewer side effects.

Clinics using lasers should have trained laser safety supervisors to reduce accidents and possibly lower insurance costs.

7.5% DEET lotion is more effective and safe at repelling mosquitoes than rosemary, citronella, and lemongrass lotions.

Combining microneedling with Q-switched laser treatment for tattoo removal did not improve results and caused more pain.

Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.

Finasteride, a drug used for certain conditions, can cause serious side effects like sexual dysfunction, suicidal thoughts, and increased diabetes risk, and there's a need for more awareness and research about these effects.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.