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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.

Understanding genes and hormones is crucial for managing male puberty and sex development disorders.

Local skin glucocorticoid production is crucial for healthy skin, and its disruption can lead to skin diseases.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.

DHT, a testosterone byproduct, causes male pattern baldness.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.

The research identified and described a gene important for hormone conversion in endangered catfish, which varies in activity during different reproductive stages and after hormone treatment.

Testosterone may slow down wound healing and increase inflammation.

Hormonal treatments are effective as a second-line option for moderate-to-severe acne in females, but should be used with caution due to health risks.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.

New hormonal treatments for enlarged prostate show promise for safer, effective non-surgical options.

Acne can be managed with various treatments and requires psychological support due to its emotional impact.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

Testosterone therapy helped 63% of androgen-deficient women grow scalp hair, but more research is needed.

Exposure to plastics may increase the risk of irregular menstrual cycles and symptoms of hormone imbalance in teenage girls.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Eclipta prostrata has many traditional uses and health benefits, but more research is needed to understand how it works and ensure it's safe.

Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.

Minoxidil effectively treats hair loss, especially androgenetic alopecia, but needs more research for better understanding.

Using rodents for research shows that health problems in the womb can cause diseases later in life.

Genes linked to wool fineness in sheep have been identified.

Men on 5-alpha-reductase inhibitors might have worse COVID-19 outcomes.

Minoxidil can reduce functions related to androgen receptors.