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The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

No consistent link between genotype and phenotype in 5-α-Reductase type 2 deficiency.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

Finasteride, when given in high oral doses to pregnant monkeys, caused genital abnormalities in male fetuses, but not in female fetuses or those exposed to intravenous finasteride.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

The enzyme type 1 5α-reductase is more active in the hair follicle's lower part than in the skin's outer layer.

The study found that two enzymes linked to hair loss are located in different parts of the scalp, supporting a common treatment's effectiveness.

New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.

The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.

Low dose finasteride decreases certain steroids, possibly increasing depression risk.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

Finasteride doesn't harm bone density in older men with BPH.

New compounds may help treat prostate cancer by reducing cell growth.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Compound 4 is a promising treatment for hair loss with low toxicity.

Ganoderma lucidum, a type of mushroom, may help treat enlarged prostate by blocking testosterone conversion.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Eriocitrin and silymarin might be effective for hair loss treatment and need more research.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Saw palmetto extract can block the enzyme that converts testosterone in pig prostate cells.

Sebocytes play a key role in controlling androgen levels in human skin.

Hair loss linked to metabolic issues and insulin resistance; early assessment may reduce future health risks.

Insulin resistance is linked to high male hormone levels in women, often seen in those with PCOS.

Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.

Preventing hair loss is more effective than regrowth; oral finasteride is a realistic option.

Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.