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Older skin has higher cancer risk due to inflammation and stem cell issues.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.

Cell aging can be both good and bad for tissue repair.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Rumex japonicus Houtt. may be an effective treatment for atopic dermatitis by reducing inflammation.

XEDAR triggers a specific signaling pathway in cells.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

A new model using mice with human hair follicles helps better understand hair loss from chemotherapy.

Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.

The skin's basement membrane is specially designed to support different types of connections between skin layers and hair follicles.

The document explains the genetic causes and characteristics of inherited hair disorders.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

Acne is linked to inflammation and insulin resistance, and is associated with various syndromes that require different treatments.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

ROR-alpha may increase the growth of certain breast cancer cells by boosting aromatase, which could affect breast cancer prognosis.

MicroRNAs are crucial in controlling cell signaling, affecting cancer and tissue regeneration.

The paper concludes that understanding melanocyte development can help in insights into skin diseases and melanoma diversity.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

Mutant mice help researchers understand hair growth and related genetic factors.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

Brain-Derived Neurotrophic Factor (BDNF) slows down hair growth and promotes hair follicle regression.

Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.