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NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Adalimumab helped control a child's severe eye disease when other treatments failed.

The conclusion is that effective cancer treatment often requires a combination of therapies, but must be carefully managed due to serious side effects and the risk of immunosuppression.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive stomach cancer.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Intralesional therapy for keratoacanthoma is effective and has fewer side effects than systemic treatments.

Oral paclitaxel plus encequidar improved tumor response and caused less neuropathy but more serious infections than intravenous paclitaxel.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

Physical symptoms in depression can reveal underlying medical conditions.

Docetaxel is safe and works well for older people with cancer, with manageable side effects.

Basal cell carcinoma mostly starts from cells in the upper skin layers, not hair follicle stem cells.

Wnt-10b is important for starting hair growth and developing hair follicles.

Melanoma development can be linked to the breakdown of skin's melanin-producing units.

Interleukin-2 treatment improved hair growth, sexual function, and reduced fungal infection in a patient with thymoma-related symptoms.

Some viruses can cause cancer by changing cell processes and avoiding the immune system; vaccines and targeted treatments help reduce these cancers.

Tempol is safe and may prevent hair loss from brain radiotherapy.

Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

Targeted cancer therapies often cause skin problems that need careful management to improve patient quality of life and treatment success.

Genotyping for NUDT15 p.Arg139Cys can help predict thiopurine side effects in Japanese IBD patients.

Keratoacanthoma comes from hair follicle cells.

A young woman had a rare skin reaction to a medication for her joint disease, and a combination therapy improved her condition.

Certain proteins help nerve cells branch, and other findings relate to cancer, stem cell behavior, and cell division.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.