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research Evaluation of TRICHONEMTM as Anti-Dandruff and Hair growth promoter in young adults
This study evaluated a herbal anti-dandruff hair wash powder, TRICHONEMTM, composed of eighteen herbal ingredients, reporting effective in vitro anti-dandruff activity and high user satisfaction in a 4-week pilot trial involving 50 women, without causing irritation.
research [Study of gonadal hormone drugs in blocking filovirus entry of cells in vitro].
This study identified several gonadal hormone drugs, including toremifene citrate, tamoxifen citrate, and clomiphene citrate, that effectively inhibited filovirus entry in a pseudovirus model.
research Kinetic analysis of LY320236: competitive inhibitor of type I and non-competitive inhibitor of type II human steroid 5α-reductase
This study found that LY320236 is a competitive inhibitor of type I and a non-competitive inhibitor of type II steroid 5alpha-reductase, indicating its potential as a dual inhibitor with differing modes of activity.
research Nonsteroidal inhibitors of human type I steroid 5-.alpha.-reductase
This research article focuses on nonsteroidal inhibitors of human type I steroid 5-alpha-reductase but reports no new results.
research ETHANOLAMINE
This paper provides a comprehensive list of drugs including Ethamolin, Placidyl, Trecator-SC, Zarontin, Peganone, Didronel, and Lodine, detailing their indications, potential interactions, and reported adverse skin reactions, but it presents no new research findings.
research Dual Tumors — Trichoadenoma of Nikolowski and Melanocytic Naevi
This case study describes an unusual instance of separate trichoadenoma and melanocytic naevi occurring simultaneously on the face, with the cause of their association remaining uncertain.
research Design, synthesis and structure-activity relationships studies on steroidal aromatase and 5α-reductase inhibitors as anti-tumors
This research investigated the design and synthesis of steroid-based compounds as aromatase inhibitors for breast cancer, finding that certain structural modifications significantly enhance their inhibitory potency.
research ALOPECIA TRIANGULAR CONGÉNITA BILATERAL EN UN NEONATO: REPORTE DE CASO
In this report, a newborn female with bilateral symmetrical alopecia lesions was diagnosed with congenital triangular alopecia, an unusual presentation, highlighting the disorder's benign nature and the importance of early recognition and conservative management.
research Compatibility of Cetirizine Hydrochloride, Dutasteride, Hydrocortisone Acetate, Nicotinamide, Progesterone, and Pyridoxine Hydrochloride in TrichoSolTM, A Natural Vehicle for Hair Solutions.
In this study, researchers assessed the physical-chemical and microbiological stability of various pharmaceutical ingredients in the vehicle TrichoSolTM, finding differing beyond-use dates for the compounds, such as 180 days for cetirizine hydrochloride, but only 90 days for progesterone at higher concentrations.
research A new catalyst for organic synthesis: mercuric triflate
This study describes Hg(OTf)2 as a new and efficient catalyst for various organic synthesis reactions, including alkyne hydration and C–C bond forming cyclizations.
research Solubilizing steroidal drugs by β-cyclodextrin derivatives
This study found that anionic HSES achieved high complexation efficiencies with various steroids, significantly enhancing their solubility, while specific β-cyclodextrin thioethers showed selective binding to testosterone and estradiol.
research BindingDB Entry 50021519: Discovery of (2S)-N-(6-Cyano-5-(trifluoromethyl)pyridin-3-yl)-3-(6-(4-cyanophenyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)-2-hydroxy-2-methylpropanamide as a Highly Potent and Selective Topical Androgen Receptor Antagonist for Androgenetic Alopecia Treatment.
research 880 Triptolide (TRP), a diterpenoid, shows a strong efficacy and a safe profile in the topical treatment of actinic keratosis lesions in a UV-B-induced mouse model
This study found that a single dose of TRP significantly reduced the number of UV-B-induced actinic keratosis lesions in a mouse model and was associated with improved skin histology and minimal side effects.
research Venous and pulmonary thromboembolism and combined hormonal contraceptives. Systematic review and meta-analysis
This study concluded that combined hormonal contraceptives containing desogestrel, drospirenone, or cyproterone acetate were associated with a higher risk of venous thromboembolism compared to those containing levonorgestrel.
research Compatibility of Caffeine Clobetasol Propionate Dutasteride Nicotinamide and Progesterone in TrichoFoam™, a Natural Vehicle for Hair Foams.
This abstract introduces TrichoFoam™, a new foaming vehicle for compounding pharmacies, designed to be a gentle, non-irritating option for alopecia treatment, acknowledging that current topical treatments are limited and oral products may cause adverse effects.
research Acute And Sub Chronic Toxicity Of Tridax Procumbens In Experimental Animals
This study found that high doses of ethyl acetate extract from Tridax procumbens can have specific toxic effects in rats, including organ damage and significant changes in some serum biochemical parameters.
research Three strands ironed closely together
In this study, researchers used iron ion coordination to successfully create a molecular knot with three organic ligand strands and eight crossings.
research Lack of a gonadal or adrenal androgenic mechanism for the hypertrichosis produced by diazoxide, phenytoin and minoxidil
These drugs cause hair growth without affecting testosterone or adrenal hormones.
research Calcipotriol/dithranol
research Rational Design and Synthesis of 4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile (PF-998425), a Novel, Nonsteroidal Androgen Receptor Antagonist Devoid of Phototoxicity for Dermatological Indications
This study suggests that PF-0998425 is an effective androgen receptor antagonist for sebum control and androgenetic alopecia with rapid metabolism reducing the risk of systemic side effects.
research From Weed to Wonder: Exploring the Multifaceted Pharmacological Actions of Tridax procumbens Linn.
This review of Tridax procumbens highlights its pharmacological and phytochemical potential, noting the presence of biologically active compounds and suggesting its value as a basis for developing new plant-based therapeutics due to its diverse medicinal properties and low toxicity.
research Novel 5α-Reductase Inhibitors: Synthesis, Structure−Activity Studies, and Pharmacokinetic Profile of Phenoxybenzoylphenyl Acetic Acids
In this study, novel substituted benzoyl benzoic acids and phenylacetic acids were potent and selective inhibitors of human steroid 5alpha-reductase type 2, with one compound showing promising bioavailability in rats for potential clinical evaluation.
research Multiple Trichofolliculomas Mimicking Multiple Trichoepitheliomas
This report describes a rare case of multiple trichofolliculomas on the face, which clinically resembled multiple trichoepitheliomas.
research The Antiandrogens
research Crystal Structure and Synthesis of 17.ALPHA.-Acetoxy-6,7-epoxypregn-4-ene-3,20-dione
A new compound was made that might help treat diseases related to male hormones.
research Acquired trichomegaly with topiramate
In this case report, the authors suggest that topiramate, used for treating bipolar disorder, may cause trichomegaly, or excessive eyelash growth, in patients.
research From Weed to Wonder: Exploring the Multifaceted Pharmacological Actions of Tridax procumbens Linn.
In this review, researchers examined Tridax procumbens for its pharmacological and phytochemical potential, highlighting its diverse medicinal benefits, low toxicity, and the presence of bioactive compounds, positioning it as a promising candidate for developing safe and affordable plant-based therapeutics.
research Synthesis, antiproliferative, acute toxicity and assessment of antiandrogenic activities of some newly synthesized steroidal lactams
research A Thallium-Based Screening Procedure to Identify Molecules That Modulate the Activity of Ca2+-Activated Monovalent Cation-Selective Channels
This study optimized a screening assay to identify molecules that inhibit or enhance TRPM5 ion channel activity, which may have implications for treating dysfunctions linked to cardiac arrhythmias and diabetes.