71 citations
,
March 1995 in “Journal of The American Academy of Dermatology” This study concluded that combining vertical and transverse sections of scalp biopsy specimens improves diagnostic yield for certain hair disorders without increasing costs.
56 citations
,
July 2005 in “Journal of The American Academy of Dermatology” This study found that vertical sections of alopecia biopsy specimens had a higher concordance rate with the original combined diagnosis compared to transverse sections alone, although both methods have their pros and cons.
33 citations
,
August 2005 in “The American Journal of Dermatopathology” This article provides departmental contact information for Dr. Dirk M. Elston at the Geisinger Medical Center and reports no research findings.
24 citations
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August 2005 in “The American Journal of Dermatopathology” This article critically assesses literature favoring horizontal over vertical sections for diagnosing scalp diseases and concludes that a qualitative, vertical approach improves diagnostic precision for alopecias.
19 citations
,
September 2011 in “Clinical and Experimental Dermatology” This study suggests that for single biopsy specimens, transverse sections may be preferable for diagnosing noncicatricial alopecia, while vertical sections may be better for suspected lichen planopilaris.
3 citations
,
January 2019 in “Indian Journal of Dermatology” This study observed that transverse sectioning of scalp biopsies may aid in diagnosing different types of alopecia by revealing distinct histopathological features like follicle miniaturization and specific inflammatory patterns.
February 2009 in “Journal of the American Academy of Dermatology” Transverse sections are better for non-scarring hair loss, vertical sections are better for lichen planopilaris, and either method works for other scarring hair loss types.
1 citations
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October 2023 in “Veterinary Dermatology” This study found that in Pomeranian dogs with alopecia X, dermoscopic evaluations can supplement diagnoses, and transverse skin biopsy sections better assess hair follicle density and identify growth arrest phases compared to longitudinal sections.
June 2023 in “Clinical Cosmetic and Investigational Dermatology” In this study, a combined technique of mini-punch grafting and follicular hair transplant was used on five patients with stable hairline vitiligo, resulting in satisfactory repigmentation and hair regrowth within the hairline while preventing hair loss and achieving repigmentation outside it.
6 citations
,
February 2020 in “Journal of Cutaneous Pathology” This case report describes the histopathological features of nevus psiloliparus in an 11-year-old girl, noting "shadow" follicular units with loosely arranged collagen and reduced elastic fibers.
17 citations
,
April 1997 in “American Journal of Dermatopathology” This report provides the first microscopic description of pachyonychia congenita-associated alopecia, identifying a combination of histological features that might be unique to this condition.
12 citations
,
August 2001 in “PubMed” This study found that contrast enhanced phototrichogram (CE-PTG) significantly improved detection of various hair types and growth stages in androgenetic alopecia compared to standard PTG and was comparable to biopsy analysis.
42 citations
,
December 1990 in “The Journal of Dermatologic Surgery and Oncology” This study found decreased hair density and altered follicular architecture in the balding frontal scalp of patients with androgenic alopecia, with increased vellus hairs noted.
5 citations
,
November 2017 in “Dermatologica Sinica” In this study, transverse sectioning of scalp biopsy samples showed higher diagnostic accuracy than vertical sectioning for noncicatricial alopecia, although both techniques are important for accurate diagnosis.
139 citations
,
July 1991 in “Journal of The American Academy of Dermatology” This article discusses the structure of hair follicles and their significance in evaluating hair disorders, but it does not report any new research findings.
12 citations
,
February 2013 in “Journal of Cutaneous Pathology” This review evaluates various biopsy protocols for alopecia diagnosis and discusses the authors' experience with the St John's protocol but presents no new clinical findings.
2 citations
,
January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” In this study on Iranian patients with non-scarring alopecia, researchers found that androgenetic alopecia was the most common subtype, with perifollicular inflammation observed more in males. They reported that transverse sectioning is generally sufficient for diagnosis, but combining with vertical sectioning provides more comprehensive information.
2 citations
,
March 2011 in “Journal of Cutaneous Pathology” The document suggests simplifying alopecia diagnosis and improving techniques for better accuracy.
January 2014 in “Pathology” The document concludes that understanding nail anatomy is key for diagnosing nail diseases, early signs of nail melanoma may allow for less aggressive treatment, and specific genetic mutations are important in thyroid cancer prognosis and treatment.
January 2014 in “Pathology” Non-scarring hair loss can be diagnosed with two 4mm punch biopsies, one cut vertically and the other transversely.
January 2014 in “Pathology” RET mutation is important in familial medullary thyroid carcinoma, and BRAF mutation in papillary thyroid carcinoma is linked to more aggressive cancer and higher death rates.
This study found that distinct hair fiber structures among blue fox, mink, and otter rabbit can be used to identify and differentiate these fur types.
2 citations
,
August 2006 in “Journal of Dermatological Science” Automated image analysis helps diagnose and monitor alopecia areata by efficiently measuring hair follicles.
1 citations
,
July 2017 in “Skin appendage disorders” A 9-year-old Hispanic girl has Uncombable Hair Syndrome, which may improve with age and biotin treatment.
January 1989 in “Clinical and Experimental Dermatology” This symposium abstract reports no new experimental results and discusses the pathophysiology of hair growth as presented at an event organized by the Institute of Dermatology.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” Examining scalp tissue under a microscope helps diagnose and understand hair loss diseases.
3 citations
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January 2018 in “Dermatology” This study found that transverse sections of scalp biopsies, particularly looking at the anagen:non-anagen hair ratio and presence of pigment casts, effectively distinguish alopecia areata from androgenetic alopecia.
January 2018 in “Figshare” This study found that transverse sections of scalp biopsies showing lower anagen:non-anagen hair ratios and presence of pigment casts help differentiate alopecia areata from androgenetic alopecia.
1 citations
,
August 2022 in “Piel” This study found a statistically significant association between dermatological manifestations with vasculonecrotic damage and increased probability of severe COVID-19 disease among patients in Guatemala.
6 citations
,
January 2017 in “International Journal of Dermoscopy” This study found that dermoscopy can identify specific features within various nail diseases that aid in early diagnosis, although further validation of these findings is needed.