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    Glossary Transmembrane Protein

    spans the entire cell membrane, facilitating transport and signaling

    A transmembrane protein, also known as an integral membrane protein, is a type of protein that spans the entire lipid bilayer of a cell membrane. These proteins play crucial roles in various cellular processes, such as transporting molecules across the membrane, acting as receptors for signaling molecules, and maintaining the cell's structural integrity.

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    Research 30 of 1000+

    1. The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss Scientific Reports · 2017 · 19 citations
    2. Male balding as a major risk factor for severe COVID-19: A possible role for targeting androgens and transmembrane protease serine 2 to protect vulnerable individuals Journal of The American Academy of Dermatology · 2020 · 6 citations
    3. Matrix-Degrading Type II Transmembrane Serine Protease Matriptase: Its Role in Cancer Development and Malignancy 2006 · 12 citations
    4. Alopecia androgênica como agravo da infecção por SARS-CoV-2 Brazilian Medical Students · 2022
    5. Role of Polycystic Ovary Syndrome in Increasing Susceptibility to COVID-19: A Biochemical and Psychological Approach International Journal of Science and Research (IJSR) · 2022
    6. Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway ˜The œAmerican journal of pathology · 2009 · 137 citations
    7. Sex differences in COVID-19: the role of androgens in disease severity and progression Endocrine · 2020 · 121 citations
    8. Cutaneous signs in COVID ‐19 patients: A review Dermatologic Therapy · 2020 · 176 citations
    9. Matriptase: Potent Proteolysis on the Cell Surface Molecular Medicine · 2006 · 165 citations
    10. Spiking dependence of SARS‐CoV‐2 pathogenicity on TMPRSS2 Journal of Medical Virology · 2021 · 30 citations
    11. Protease activity, localization and inhibition in the human hair follicle International Journal of Cosmetic Science · 2013 · 11 citations
    12. Roles of existing drug and drug targets for COVID-19 management Metabolism Open · 2021 · 26 citations
    13. Ichthyosis, Follicular Atrophoderma, and Hypotrichosis Caused by Mutations in ST14 Is Associated with Impaired Profilaggrin Processing Journal of Investigative Dermatology · 2008 · 99 citations
    14. A novel mutation in ST14 at a functionally significant amino acid residue expands the spectrum of ichthyosis-hypotrichosis syndrome Orphanet Journal of Rare Diseases · 2017 · 11 citations
    15. LEKTI: Netherton Syndrome and Atopic Dermatitis InTech eBooks · 2013 · 1 citations
    16. Intramembrane Proteolysis of Astrotactins Journal of Biological Chemistry · 2017 · 8 citations
    17. Matriptase-2, A Novel Suppressor of Hepcidin. Blood · 2009
    18. Delineation of Matriptase Protein Expression by Enzymatic Gene Trapping Suggests Diverging Roles in Barrier Function, Hair Formation, and Squamous Cell Carcinogenesis American Journal Of Pathology · 2006 · 100 citations
    19. Targeting host cell proteases as a potential treatment strategy to limit the spread of SARS‐CoV‐2 in the respiratory tract Pharmacology Research & Perspectives · 2020 · 15 citations
    20. Matriptase Expression and Zymogen Activation in Human Pilosebaceous Unit 2013 · 9 citations
    21. Perspective Chapter: Repurposing Natural Products to Target COVID-19 – Molecular Targets and New Avenues for Drug Discovery IntechOpen eBooks · 2022 · 1 citations
    22. Are the cutaneous manifestations during or due to SARS-CoV-2 infection/COVID-19 frequent or not? Revision of possible pathophysiologic mechanisms Inflammation Research · 2020 · 82 citations
    23. Nagashima-Type Palmoplantar Keratosis: A Common Asian Type Caused by SERPINB7 Protease Inhibitor Deficiency Journal of Investigative Dermatology · 2014 · 24 citations
    24. The protease corin regulates electrolyte homeostasis in eccrine sweat glands PLoS biology · 2021 · 10 citations
    25. Overexpression of Lnk in the Ovaries Is Involved in Insulin Resistance in Women With Polycystic Ovary Syndrome Endocrinology · 2016 · 11 citations
    26. Deficiency of the human cysteine protease inhibitor cystatin M/E causes hypotrichosis and dry skin Genetics in medicine · 2018 · 10 citations
    27. Cardiac and Renal SARS-CoV-2 Viral Entry Protein Regulation by Androgens and Diet: Implications for Polycystic Ovary Syndrome and COVID-19 International Journal of Molecular Sciences · 2021 · 3 citations
    28. A case of <i>MBTPS1</i>‐related disorder due to compound heterozygous variants in <i>MBTPS1</i> gene: Genotype–phenotype expansion and the emergence of a novel syndrome American journal of medical genetics. Part A · 2023
    29. Updated strategies for the management, pathogenesis and molecular genetics of different forms of ichthyosis syndromes with prominent hair abnormalities Archives of dermatological research · 2017 · 3 citations
    30. Functional identification of the phosphorylation sites of Arabidopsis PIN-FORMED3 for its subcellular localization and biological role The Plant Journal · 2012 · 47 citations