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GlossaryTMPRSS2 (Transmembrane Protease Serine 2)

enzyme aiding viral entry into human cells

TMPRSS2 stands for Transmembrane Serine Protease 2, an enzyme that plays a role in the activation of certain proteins by cutting them at specific sites. It is notably involved in the process by which the SARS-CoV-2 virus, responsible for COVID-19, enters human cells, making it a target for therapeutic interventions.

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Male Balding as a Major Risk Factor for Severe COVID-19: A Possible Role for Targeting Androgens and Transmembrane Protease Serine 2 to Protect Vulnerable Individuals

research Male Balding as a Major Risk Factor for Severe COVID-19: A Possible Role for Targeting Androgens and Transmembrane Protease Serine 2 to Protect Vulnerable Individuals

6 citations , September 2020 in “Journal of The American Academy of Dermatology”

Severe male balding may increase the risk of serious COVID-19, and treatments that reduce androgens or block a specific enzyme might help protect these individuals.

research Cutaneous Signs in COVID-19 Patients: A Review

176 citations , May 2020 in “Dermatologic Therapy”

COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.

research ACE1 rs1799752 Polymorphism Is Not Associated With Long-COVID Symptomatology In Previously Hospitalized COVID-19 Survivors

6 citations , December 2022 in “Journal of Infection”

The ACE1 gene variant doesn't affect long-COVID symptoms.

Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

research Immunoreactivity of the SARS-CoV-2 Entry Proteins ACE-2 and TMPRSS-2 in Murine Models of Hormonal Manipulation, Aging, and Cardiac Injury

5 citations , December 2021 in “Scientific Reports”

Age affects how certain proteins involved in COVID-19 infection are expressed in mice, but sex hormones and heart injury do not.

research The Secret Identities of TMPRSS2: Fertility Factor, Virus Trafficker, Inflammation Moderator, Prostate Protector and Tumor Suppressor

16 citations , August 2021 in “Tumor Biology”

TMPRSS2 helps viruses enter cells and protects the prostate from inflammation-related cancer.

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community Exosomes - do they work as results look promising?

in Treatment 2 upvotes 5 years ago

Exosomes are being considered for hair regrowth, with some users reporting initial improvement. One user moved on to using dutasteride and oral minoxidil with positive results.