research Health-Related Quality of Life Questionnaire for Polycystic Ovary Syndrome (PCOSQ-50): Development and Psychometric Properties
The PCOSQ-50 is a valid and reliable questionnaire for measuring quality of life in Iranian women with PCOS.
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research Androgen Antagonists in Androgen Target Tissues
Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.
research Cloning of the Human Phenol Sulfotransferase Gene Family: Three Genes Implicated in the Metabolism of Catecholamines, Thyroid Hormones, and Drugs
Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.
research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research Testosterone Therapy in Men: Clinical and Pharmacological Perspectives
Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research Modulating Mesenchymal Stem Cell Behavior Using Human Hair Keratin-Coated Surfaces
Coating surfaces with human hair keratin improves the growth and consistency of important stem cells for medical use.
research The Effects of High-Intensity Interval Training on Vaspin, Adiponectin, and Leptin Levels in Women with Polycystic Ovary Syndrome
High-intensity interval training improves certain hormone levels and lipid profiles in women with PCOS.
research Identification of Telogen Markers Underscores That Telogen Is Far from a Quiescent Hair Cycle Phase
Telogen is an active phase with important biological processes, not a resting phase.
research The TOR–Auxin Connection Upstream of Root Hair Growth
High energy boosts root hair growth in plants, while low energy stops it.
research Cutaneous Wound Healing: Canine Allogeneic ASC Therapy
Using stem cells from fat tissue can significantly improve wound healing in dogs.
research Peripheral Blood Gene Expression in Alopecia Areata Reveals Molecular Pathways Distinguishing Heritability, Disease, and Severity
Blood tests can help understand the genetic differences in people with alopecia areata, including how severe it is and if it's inherited.
research Dermatological Illnesses of Immigrant Poultry-Processing Workers in North Carolina
All immigrant workers in the study had skin problems, with fungal nail infections, athlete's foot, and acne or folliculitis being most common, affecting their quality of life, yet they didn't seek medical help.
research Relating Neurosteroid Modulation of Inhibitory Neurotransmission to Behavior
Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.
research The Disrupted Balance Between Hair Follicles and Sebaceous Glands in Hoxc13-Ablated Rabbits
Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.
research A Perspective on the Evolving Landscape in Male Reproductive Medicine
Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Illness Perception in Patients with Androgenetic Alopecia and Alopecia Areata in China
Illness perception affects mental health and quality of life in Chinese alopecia patients.
research Recent Discoveries and Developments of Androgen Receptor-Based Therapy for Prostate Cancer
New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Repurposing Kir6/SUR2 Channel Activator Minoxidil to Arrest Growth of Gynecologic Cancers
Minoxidil can stop the growth of ovarian cancer cells without harming the heart.
research PCOS: Update and Diagnostic Approach
The document concludes that more research is needed to fully understand the causes of PCOS.
research Development of Chinese Version of Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire
The Chinese version of the PCOS quality of life questionnaire is reliable and valid for Chinese-speaking women with PCOS.
research Applications and Implications of Heparin and Protamine in Tissue Engineering and Regenerative Medicine
Heparin and protamine are promising in tissue repair and organ regeneration, including skin and hair.
research Current Concepts in Aesthetic Endocrinology
Hormones affect skin aging and fat distribution, and treatments can help, but only minoxidil is proven for female hair loss.
research Ranitidine And Finasteride Inhibit The Synthesis And Release Of Trimethylamine N-Oxide And Mitigate Its Cardiovascular And Renal Damage Through Modulating Gut Microbiota
Ranitidine and finasteride lower TMAO levels, reducing heart and kidney damage by changing gut bacteria.
research New Biomarkers to Evaluate Hyperandrogenemic Women and Hypogonadal Men
The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.
research Reversal of Alopecia Universalis by Tofacitinib: A Case Report
Tofacitinib, an arthritis drug, helped hair growth in alopecia universalis but long-term safety needs more research.
research Targeted Expression of SV40 T Antigen in the Hair Follicle of Transgenic Mice Produces an Aberrant Hair Phenotype
SV40 T antigen in hair follicles causes abnormal hair and health issues in mice.
research Janus Kinase Inhibitors For Alopecia Areata
JAK inhibitors effectively improve hair regrowth in alopecia areata with an acceptable safety profile.