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Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Cell-based therapies show promise for treating Limbal Stem Cell Deficiency but need more research.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

Skin-derived stem cells can become various cell types, including germ cell-like and oocyte-like cells.

Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.

Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.

FGF-1 causes spiral ganglion neurites to branch more.

Hair restoration has evolved from surgery to drugs to potential gene therapy, with improved results and ongoing research driven by high demand.

Rat dermal papilla cells have unique genes crucial for hair growth.

Transfollicular drug delivery is promising but needs more research to improve and understand it better.

Nanotechnology is improving drug delivery and targeting, with promising applications in cancer treatment, gene therapy, and cosmetics, but challenges remain in ensuring precise delivery and safety.

The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.

Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

Keratin gene expression helps understand different types of skin cells and their development, and should be used carefully as biological markers.

A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.

Activating TRPV3 reduces skin oil production and increases inflammation, potentially causing dry skin issues.

Ultrasound can help deliver genes to cells to stimulate tissue regeneration and enhance hair growth, but more research is needed to perfect the method.

Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

BMAL1 and Period1 genes can influence human hair growth.

Scientists successfully created mouse hair proteins in the lab, which are stable and similar to natural hair.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.