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RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.

Cutaneous gene therapy could become a viable treatment for skin and hair disorders with improved vector development and gene expression control.

Advancements in nanoformulations for CRISPR-Cas9 genome editing can respond to specific triggers for controlled gene editing, showing promise in treating incurable diseases, but challenges like precision and system design complexity still need to be addressed.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

Activating the GDNF-GFRα1-RET signaling pathway could potentially promote skin and limb regeneration in humans and could be used to treat hair loss and promote wound healing.

A lotion with natural extracts significantly sped up hair growth in women with hair loss from chemotherapy.

Overexpressing Merkel cell virus proteins in human hair follicles can create clusters of cells that resemble Merkel cell cancer.

Body and beard hair can be used for hair restoration in severely bald patients, but the technique is complex and costly.

Hair transplantation in East Asians needs special techniques to ensure natural results and prevent complications due to their unique hair and scalp characteristics.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

The endobrow-midface lift is a safe and effective way to rejuvenate the upper face with minimal complications and rare temporary hair loss.

Both Follicular Unit Transplantation (FUT) and Follicular Unit Excision (FUE) are effective hair transplant methods; the best choice depends on the patient's needs and the surgeon's preference.

Esthetic surgery complications can include infections, nerve injury, and more; proper evaluation and technique help prevent them.

Cathepsin L is essential for normal hair growth and development.

Exposure to finasteride in the womb caused lasting reproductive issues in male rats.

New alopecia treatments aim for better results and fewer side effects.

Face-lifts can lead to complications like bleeding, nerve injury, skin death, hair loss, and rare infections, with careful surgery reducing risks.

Use finasteride, minoxidil, and follicular unit transplantation for hair loss treatment.

Teriflunomide is effective and generally safe for treating relapsing-remitting multiple sclerosis.

The document concludes that understanding how adult stem and progenitor cells move is crucial for tissue repair and developing cell therapies.

Men prefer less invasive cosmetic procedures and need different treatment approaches than women.

Individualized assessment and meticulous planning are crucial for successful brow and upper eyelid surgery.

Hair restoration surgery redistributes existing hair to achieve a natural look, with visible regrowth in 3-4 months and rare complications, mostly aesthetic.

Hair transplantation is effective for baldness, with new methods improving results, but staying updated is crucial for patient outcomes.

Several new treatments for different types of hair loss show promise in improving patient quality of life.

Follicular Unit Transplantation is a precise hair restoration technique that requires careful planning and a skilled team, and Follicular Unit Extraction offers a less invasive option.

Beard hair can be used for hair transplants in severe alopecia cases, with minimal complications and good results.

Lasers are effective for some skin conditions but can cause side effects like scarring and pigment changes; careful selection is important, and botulinum toxin type A is successful in reducing sweat in palmar hyperhidrosis.

The KNU implanter for hair transplants showed a high survival rate of 90%+ for transplanted hairs after 6 months, with benefits like natural hair direction and fewer scars.