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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

ARL15 is important for fat cell development and the release of the hormone adiponectin.

Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

New treatments for skin conditions related to the sebaceous gland are being developed based on current research.

Eating dairy and high glycemic foods may increase the risk of acne.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

There is no cure for myotonic dystrophy type 1, so treatment focuses on managing symptoms and complications.

Altering SSAT affects fat metabolism and body fat in mice.

Understanding how DHT works is important for diagnosing and treating hormone-related disorders.

Alkaline Ceramidase 1 prevents early hair loss in mice by keeping hair follicle stem cells balanced.

Transplanted rat hair follicles grew hair and had increased but not fully restored nerve connections in mice.

Future hair cosmetics will be safer and more effective.

VDR regulation varies by tissue and is crucial for its biological functions.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.

Men and women respond differently to drugs for COVID-19, high cholesterol, and diabetes, which suggests a need for personalized treatments.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

In Japan, sex reassignment surgery for gender identity disorder faces challenges and needs better medical support and education.

The meeting showcased rare skin disease cases, highlighting the need for accurate diagnosis and treatment.

Hdac1 and Hdac2 help maintain and protect the cells that control hair growth.

The method safely and efficiently delivers genes to the skin but may not work for conditions needing high levels of gene products.

Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.

The document concludes that mesotherapy can be effective for skin and hair treatments, but more research is needed to confirm its safety and effectiveness.