9 citations
,
March 2011 in “Current Pharmaceutical Biotechnology” This review discusses current stem cell technologies, their potential therapeutic uses, and imaging techniques for tracking transplanted cells, without reporting new experimental results.
January 2025 in “Sustainable food connect.” This review discusses gene editing techniques for breeding livestock, birds, and fish, concluding that they are key to advancing animal production by improving traits and efficiency.
26 citations
,
April 1998 in “Journal of Investigative Dermatology” This study in transgenic mice found that the combination of SPF 15 sunscreen and a UVA filter provided strong protection against UVA-induced elastin promoter activation and thus may reduce photoaging.
October 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” This study demonstrates that using a K15 promoter-driven GFP labeling technique allows for the identification and characterization of epithelial stem cells in adult human hair follicles.
132 citations
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June 2016 in “Cell and Tissue Research” This review discusses recent advancements in scar reduction techniques, highlighting promising therapeutic targets and the role of Wnt/β-catenin signaling in promoting scarless wound healing, but reports no new clinical results.
This study reviewed various methods and techniques aimed at overcoming limitations in culturing human hair follicles, specifically focusing on restoring the inductivity of hair follicle cells for successful hair regeneration.
September 2023 in “Biomedical Optics Express” This study used non-invasive imaging techniques to assess hair follicle characteristics in AGA mice, revealing delayed hair shaft alternation and growth stages, as well as testosterone-induced follicle miniaturization, offering potential methods for evaluating AGA on human scalps in vivo.
This review discusses the dynamic behavior of immune cells in skin immune responses using intravital imaging in mice and reports no new clinical results.
24 citations
,
May 2021 in “Nature Communications” In this study, a dual recombinase-mediated genetic system showed that cavity macrophages accumulate on the surface of visceral organs during lung and liver injury but do not penetrate or contribute to tissue repair.
This study presents a two-photon imaging method to visualize low-threshold mechanoreceptor axon terminals in live mouse forepaw skin, enabling repeated high-resolution imaging to study sensory circuits during development and adulthood.
14 citations
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September 2010 in “Annals of Plastic Surgery” This article reviews recent advancements in understanding hair follicle biology, with a focus on the potential for gene therapy in treating alopecia, but it reports no new research findings.
17 citations
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November 2017 in “PLoS ONE” This study observed dynamic behaviors such as cluster formation, migration, and active proliferation of transplanted bone marrow cells in a mouse model, providing insight into cellular-level changes post-transplantation.
17 citations
,
January 2007 in “Annals of Medicine” This review discusses advancements and challenges in cutaneous gene therapy using direct and indirect techniques, noting that while clinical translation has begun, further developments are essential for progress.
11 citations
,
September 2023 in “ACS Omega” This review highlights the rapid advancements in 3D bioprinting techniques, emphasizing their role in enhancing regenerative therapy, drug delivery, and bioengineering applications while addressing current challenges in bioink formulation and bioprinting stability.
10 citations
,
November 2019 in “Cold Spring Harbor Perspectives in Biology” This review discusses how recent advances in live imaging have revealed the dynamic and adaptable nature of stem cells during various biological processes, and reports no clinical results.
94 citations
,
July 2003 in “Journal of biological chemistry/The Journal of biological chemistry” This study found that continuous expression of epidermal growth factor in transgenic mice prevented hair follicles from entering the catagen phase, implicating EGF as a crucial regulator in hair cycle progression.
11 citations
,
February 2011 in “International Journal of Molecular Sciences” This article reviews sPLA2-mediated phospholipid metabolism using sPLA2 transgenic/knockout mice and lipid mass spectrometry, offering insights into the distinct roles of sPLA2 enzymes in various biological events.
4 citations
,
October 2021 in “Scientific Reports” This study found that NKIRAS2 expression affects skin tumor suppression and HRAS-driven transformation in mice, indicating its role in carcinogenesis depends on expression level and cellular context.
28 citations
,
April 2021 in “Biomedicines” This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.
2 citations
,
September 2014 in “The American Journal of Cosmetic Surgery” This review discusses advancements and challenges in laboratory-based tissue-expansion and transplantation techniques for facial wound healing, noting potential for stem cell therapies but highlighting the ongoing absence of skin features like hair follicles in cultured grafts.
January 2017 in “Brazilian Journal of Pharmaceutical Sciences” This study identified neprilysin as a potential target of the pharmacological agent arteannuin, which may guide future research into its clinical applications, although experimental verification is needed.
47 citations
,
April 2000 in “The American journal of pathology” This study found that overexpressing human Bcl-2 in mice protected epidermal keratinocytes from UVB-induced apoptosis but unexpectedly increased apoptosis during hair follicle regression and chemotherapy.
23 citations
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May 2013 in “Virology” This study found that HPV16 oncogene expression in multipotent epithelial stem cells led to abnormal mobilization, altering their quiescence without affecting other stem cell markers, suggesting a distinct stem cell compartment.
14 citations
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November 2018 in “Journal of Cosmetic Dermatology” In this study, patients with androgenetic alopecia treated with platelet-rich plasma showed increased hair density and improved hair quality over six months, with no notable adverse effects, indicating that PRP may be an effective treatment option for this condition.
29 citations
,
January 2010 in “Methods in Enzymology” This review discusses five genetic fate mapping methods used to study cell behaviors during development and regeneration, detailing the necessary tools and considerations without reporting new experimental results.
2 citations
,
May 2023 in “Veterinary Pathology” This article outlines methods to study the skin and its molecular traits, focusing on interpretation and techniques applicable to mouse models, including diverse assays and approaches like electron microscopy and large-scale lipid analyses.
1 citations
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January 2020 This study found that Ift20 is essential for hair follicle stem cell identity and hair regrowth, and it regulates keratinocyte migration during wound healing through focal adhesion integrin recycling, independently of ciliogenesis.
92 citations
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April 2021 in “Pharmaceutics” This review discusses the applications and challenges of lipid nanosystems in various fields, comparing techniques for evaluating nanoparticle properties, and reports no new experimental results.
140 citations
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February 2020 in “Frontiers in Plant Science” This article discusses the potential of RNA-based biopesticides for sustainable agriculture and reports no new experimental results; it highlights the need for improved delivery systems and regulatory development to enhance deployment.
20 citations
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October 2008 in “Archives of dermatological research” This study found that angiogenin is expressed in human dermal papilla cells, where it might stimulate hair growth by promoting cell proliferation and local skin angiogenesis.