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Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.

The FUL hair restoration technique is better for aesthetics and causes less scarring.

Skin can become dry and thick in hypothyroidism.

Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.

Fully regenerating human hair follicles not yet achieved.

Hormone imbalance is linked to Hidradenitis Suppurativa, a skin condition, and treatments like anti-androgenic therapy and metformin can help. It's also suggested to check patients for insulin resistance and Polycystic Ovary Syndrome.

Late diagnosis of congenital adrenal hyperplasia can greatly affect physical development, gender identity, and sexual health.

Women with PCOS have distinct retinal changes compared to healthy women.

Women experience more side effects and have worse blood pressure control from hypertension treatments than men, despite using different medications.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Human hair follicle dermal cells can effectively replace other cells in engineered skin.

The document concludes that cosmetic surgery is still mainly a practice for women and the gender gap in this field is expected to continue.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

Women with androgenetic alopecia have fewer terminal hairs, phenol in nail surgery is safe, and a new hair transplant method is faster and less damaging.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Human pluripotent stem cells could be used to make platelets for medical use, but safety, effectiveness, and cost issues need to be resolved.

PNKP is essential for keeping adult mouse progenitor cells healthy and growing normally.

A genetic region near the PAX1 gene is linked to a higher risk of scoliosis in females.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.