TLDR Many children and teens referred to gender services receive hormone treatments, but more research is needed on their long-term care and outcomes.
This systematic review examined the care pathways of 6133 children and adolescents (median age 14-16) referred to specialist gender services across 23 studies from nine countries. It found that 36% received puberty suppression, 51% received masculinising or feminising hormones, 68% received either or both treatments, and 16% underwent surgery. The review highlighted a lack of systematic reporting on the full care pathways and psychological care, with insufficient or unclear follow-up in many studies. It emphasized the need for prospective studies with long-term follow-up to better understand the outcomes and psychological care provided to this population.
116 citations
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December 2013 in “The Journal of Pediatrics” Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.
7 citations
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January 2019 in “Headache” Hormone therapy may increase migraines in transgender women and decrease them in transgender men; more research is needed on migraine management in transgender individuals.
5 citations
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September 2021 in “Southern African Journal of Hiv Medicine” The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.
September 2021 in “Physiology News” Air Vice-Marshal Sir Ralph Jackson significantly advanced dialysis technology in the UK.
September 2021 in “Physiology News” Addressing underrepresentation in Parkinson's research is crucial for better treatments and understanding.
2295 citations
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August 2012 in “The international journal of transgenderism/International journal of transgenderism” The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.