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In this study, researchers identified significant differences in protein expression patterns in scalps affected by central centrifugal cicatricial alopecia, notably upregulation of immune pathways and fibrosis markers and downregulation of metabolic proteins, suggesting unique disease mechanisms and potential therapeutic targets.

In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.

This review examines the complex role of the Ectodysplasin-A pathway in skeletal morphogenesis, emphasizing its interaction with other key signaling pathways, and reports no new experimental findings.

This study found that silencing the circular RNA circNlgn in mice reduced doxorubicin-induced cardiofibrosis and cardiomyocyte apoptosis, suggesting potential therapeutic strategies for minimizing heart-related side effects in cancer treatment.

This study found that certain lncRNA gene polymorphisms in HOTAIR and MALAT1 are associated with increased susceptibility to systemic lupus erythematosus, potentially informing clinical applications.

In this study, researchers demonstrated that CD4 T cells from skin-draining lymph nodes in mice with alopecia areata can transfer the disease to recipient mice, revealing a critical role for CD4 T cells in disease development and suggesting potential therapeutic targets.

In this study, Hedgehog signaling in dermal papilla fibroblasts was found to accelerate hair growth and induce follicle multiplication in mice via the SCUBE3/TGF-β pathway, with some effects observed in human scalp hair follicles.

This review discusses the metabolic and physiological mechanisms that maintain hematopoietic stem cell function, particularly focusing on oxygen and energy homeostasis, but it reports no new experimental results.

This review discusses the roles of key epithelial-mesenchymal transition factors and potential therapeutic opportunities involving cancer metabolic pathways, reporting no new clinical results.

This review explores the diverse physiological roles of the vitamin D endocrine system, discussing current research on receptor structure, transcription details, murine models, and alternative receptors, but reports no new findings.

This study establishes a catalog of human type I hair keratins and identifies their specific roles and expression patterns during hair differentiation and growth in scalp follicles.

This review discusses how dehydroepiandrosterone (DHEA) may exert its biological effects through multiple receptors and reports no new clinical results.

This study found that the p63 transcription factor plays a role in epidermal morphogenesis by regulating Satb1 expression, impacting chromatin architecture and gene expression in epidermal progenitor cells.

This study found that endogenous activin plays a crucial role in wound healing and scar formation, as its inhibition led to delayed wound healing and reduced scar size in transgenic mice.

This study found that thyroid-stimulating hormone receptors are functionally expressed in various skin cells, implying potential physiological and pathological roles in skin, especially in conditions like autoimmune diseases.

Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.

Zeb2 is crucial for nerve repair by controlling Schwann cell function.

Alopecia areata is caused by an immune response, and targeting immune cells might help treat it.

This study identified specific gene expression profiles during the intestinal regeneration of sea cucumbers, highlighting potential novel genes and advancing the understanding of regenerative biology in echinoderms.

This study found that methylprednisolone can block IgG-induced keratinocyte detachment in an animal model of pemphigus vulgaris, potentially by increasing the synthesis and modifying adhesion molecules.

This study found that inhibiting TGF-β receptors in adult dermal fibroblasts restored their function and increased resistance to Staphylococcus aureus infection by enhancing their adipogenic and antimicrobial capabilities.

Thyroid-stimulating hormone affects hair follicles but doesn't change hair growth or color.

This study characterized a new human keratin, hK6irs1, specifically found in the inner root sheath of hair follicles, which suggests its role in the structural integrity and guidance of growing hair shafts.

This study discovered that a network controlled by the gene p63 is crucial for keratinocyte differentiation and is linked to MYC through cell adhesion-related pathways.

This study demonstrated that AtVLN4 plays a role in root hair growth by regulating actin organization in a calcium-dependent manner.

This study identified gene expression differences between dermal papilla cells from primary and secondary hair follicles in Cashmere goats, highlighting their roles in hair follicle morphogenesis.

The research identified six functional hair keratin genes and four pseudogenes, providing insights into hair formation and gene organization.

This study found that mutations in the FGF5 gene are the primary genetic factor causing long hair in domestic cats through an autosomal recessive mechanism.

In this study, nitrogen starvation in Chlorella sp. FC2 IITG led to increased lipid accumulation by altering the expression of enzymes involved in various metabolic pathways, suggesting potential for genetic engineering of microalgae.

This study found that the differential expression of α- and β-keratin genes in feathers may explain their morphological and structural diversity, highlighting the chicken as a model for studying keratin-related diseases.