17 citations
,
August 1979 in “Journal of The American Academy of Dermatology” This study found that a histochemical stain using 4-dimethyl-aminocinnamaldehyde effectively distinguishes between plucked anagen and telogen hairs by causing the root ends of anagen hairs to develop a red color.
16 citations
,
February 2019 in “Pediatric Blood & Cancer” In this study, 96% of children with CNS tumors receiving MAPK and mTOR inhibitors experienced common, treatable skin reactions, occasionally requiring therapy adjustments.
16 citations
,
October 2015 in “Photochemistry and photobiology” This study found that higher concentrations of copper (II) ions in human hair increase protein oxidative modification, contributing to hair damage regardless of UV exposure and pigmentation level.
16 citations
,
August 2014 in “Archives of Pharmacal Research” This study found that surface-modified liquid crystalline nanoparticles significantly enhanced skin permeation of finasteride and dutasteride compared to unmodified nanoparticles, suggesting potential for improved treatment efficacy in androgenetic alopecia.
15 citations
,
January 2024 in “The AAPS Journal” This study demonstrates that bioequivalence for proposed 50-mg ritlecitinib capsules versus clinical 100-mg capsules can be supported using a PBPK model-based biowaiver, achieving over 90% probability of success.
15 citations
,
June 2018 in “Journal of Chromatographic Science” This study successfully developed a method to measure four flavonoids from Platycladus orientalis leaves in rat plasma, which was used in a pharmacokinetic study on healthy rats.
15 citations
,
October 2017 in “Dermatologic Clinics” This abstract discusses advancements in hair transplantation technology, highlighting the role of robotics and follicular unit extraction/grafting in achieving excellent clinical outcomes, with adjuvant treatments like platelet-rich plasma, lasers, and stem cells potentially improving the durability and appearance of results.
15 citations
,
September 2017 in “Dermatologic Surgery” This literature review found that chemical peels are effective for treating various skin conditions in men, such as acne, rosacea, and photodamage, and noted that men may require more treatments or stronger peels due to their skin's characteristics.
15 citations
,
September 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses OCD spectrum disorders with dermatological symptoms, emphasizing their clinical features, neurobiology, and treatment options, while noting the need for more controlled studies.
15 citations
,
February 2013 in “Pharmaceutical nanotechnology” This study found that invasomes enhanced the iontophoretic transdermal delivery of finasteride in rabbits, increasing AUC and T1/2 compared to oral suspension.
15 citations
,
July 1991 in “International Journal of Dermatology” This article discusses the technique of laser Doppler velocimetry for measuring cutaneous blood flow and does not report new research findings.
14 citations
,
May 2005 in “Farmaco” This study developed a high performance capillary electrophoresis method, validated for both legal and illicit minoxidil-based products, to confirm minoxidil's presence alongside known impurities.
14 citations
,
January 2001 in “Clinical chemistry” This article discusses the potential use of hair fibers to noninvasively measure polyamine concentrations as a marker of tumor growth, but reports no new clinical findings.
13 citations
,
October 2015 in “Journal of the European Academy of Dermatology and Venereology” The document concludes that early recognition and appropriate treatment of red scalp, red ear, and red scrotum syndromes can lead to remission.
13 citations
,
December 2013 in “Chemistry Central Journal” This study developed an inexpensive method to provide initial data on both the photostability and toxicity of pure active principles and their photodegradation products.
13 citations
,
March 2013 in “Dermatologic Surgery” This review discusses the evolution and current practices of Follicular Unit Extraction (FUE) in hair restoration surgery, reporting comparable patient outcomes to Follicular Unit Transplantation (FUT), though noting controversies in its adoption.
13 citations
,
May 1996 in “Archives of Disease in Childhood” This study found that patients with non-classical 21-hydroxylase deficiency do not appear to be at risk of short adult stature despite increased bone age in childhood.
13 citations
,
March 1990 in “JAMA” This study found that in a small cohort of patients with infections, tumor necrosis factor levels varied, challenging the interpretation that these levels are transient in gram-negative sepsis.
12 citations
,
December 2016 in “International journal of nursing practice” This study examined symptom experiences and management strategies among Puerto Rican children undergoing cancer treatments, highlighting that irritability, nausea, and hair loss were the most common symptoms reported by mothers.
12 citations
,
June 2010 in “Journal of dermatology” This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.
12 citations
,
March 1995 in “Journal of the American Chemical Society” Finasteride modifies 5-alpha-reductases through a two-step process, affecting inhibitor potency and possibly causing side effects.
12 citations
,
January 1981 in “Springer eBooks” Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.
11 citations
,
January 2020 in “Micro and Nanosystems” This study found that transethosomal gel loaded with propranolol hydrochloride prolonged drug release and increased peak plasma concentration compared to an oral tablet, suggesting a promising alternative for delivery.
11 citations
,
November 2018 in “Journal of the American Academy of Dermatology” This study found that among patients with alopecia areata treated with the JAK inhibitor tofacitinib, 34% achieved complete regrowth of eyebrows and 39% achieved complete regrowth of eyelashes, highlighting differences in treatment responses across hair-bearing sites.
11 citations
,
October 2015 in “Clinical and Experimental Dermatology” This study found that an extract from the root of Sophora flavescens Aiton significantly improved hair growth in patients with androgenetic alopecia over 6 months.
11 citations
,
May 2015 in “Stem Cells Translational Medicine” This study found that megestrol acetate increases the proliferation, migration, and adipogenic differentiation of adipose-derived stem cells through glucocorticoid receptor phosphorylation.
11 citations
,
January 1993 in “Dermatology” In this study, researchers found histopathological similarities between L-tryptophan eosinophilic myalgia syndrome and idiopathic eosinophilic fasciitis, with certain unique inflammatory features present in the former.
10 citations
,
September 2020 in “Archives of Dermatological Research” Both methods improve hair density and thickness; double-spin may be more effective.
10 citations
,
August 2015 in “Journal of biophotonics” This study found that applying benzyl nicotinate on open hair follicles led to a significant increase in blood flow, highlighting the role of the follicular pathway in epidermal penetration.
10 citations
,
August 2012 in “Clinical Pharmacokinectics” This study found that type 2 diabetes mellitus does not affect the pharmacokinetics of metformin in obese pregnant women with PCOS, suggesting no need for dosage adjustments.